Illustration of SpaceOAR Hydrogel

Clinical Results

SpaceOAR™ Hydrogel



US Pivotal Trial

Creating more space between the prostate and rectum can result in a significant reduction in rectal radiation. This reduction in rectal radiation can help reduce late rectal toxicity, which can improve quality of life.1.2

US Pivotal Trial. 73% less rectal radiation, 75% less rectal toxicity, better quality of life


Doctor in surgery

SpaceOAR™ Hydrogel is associated with lower rectal toxicity and higher bowel quality of life in late follow-up3

Systematic review & meta-analysis

 

DOWNLOAD ANALYSIS

 



SpaceOAR Hydrogel has been shown to help minimize side effects

73% relative reduction in rectal V70, 0% late grade 2+ rectal toxicity, 70% less decline in bowel quality of life, 60% reduced likelihood of decline in urinary quality of life,  67% retained sexual function




Real-world data shows how different treatment approaches can utilize SpaceOAR Hydrogel



Early Tolerance and Tumor Control Outcomes
Multi-institute phase 2 trial
Dosimentric Feasibility




Role for Rectal Spacer in the Radiotherapeutic Management of Prostate Cancer

Michael J. Zelefsky, MD, presents the Role for Rectal Spacer in the Radiotherapeutic Management of Prostate Cancer on Grand Rounds in Urology

 

LEARN MORE

 



SpaceOAR Hydrogel has been featured in numerous peer-reviewed studies


 
 

SpaceOAR Vue Hydrogel

A next-generation hydrogel spacer that is visibly different
 


References
  1. Quinn TJ, Daignault-Newton S, Bosch W, et al. Who benefits from a prostate rectal spacer? Secondary analysis of a Phase III trial. Pract Radiat Oncol. 2020 May-Jun;10(3):186-94.
  2. Hamstra DA, Mariados N, Sylvester J, et al. Continued benefit to rectal separation for prostate radiation therapy: Final results of a phase III trial. Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):976-85.
  3. Miller LE, Efstathiou JA, Bhattacharyya SK, et al. Association of the placement of a perirectal hydrogel spacer with the clinical outcomes of men receiving radiotherapy for prostate cancer: a systematic review and meta-analysis. JAMA Netw Open. 2020 Jun;3(6):e208221.
  4. Hamstra DA, Mariados N, Sylvester J, et al. Sexual quality of life following prostate intensity modulated radiation therapy (IMRT) with a rectal/prostate spacer: Secondary analysis of a phase 3 trial. Pract Radiat Oncol. 2018;8(1):e7-e15. 
Top