Investigator Sponsored Research
 Program
Overview
Submission
Process
Frequently Asked Questions
  

Investigator Sponsored Research Program

The Investigator-Sponsored Research (ISR) Program represents an important portion of medical research. The ISR Program serves as a conduit between Boston Scientific and external researchers to expand research.

Boston Scientific provides support for research that advances medical and scientific knowledge about our products. This global program is open to all qualified researchers who are interested in conducting research of value to BSC as determined by an independent ISR grant committee.

SUBMIT AN ISR REQUEST


After reading the Submission Process, log-in to submit or edit your proposal

ASK A QUESTION


If you still have questions after reading over the Frequently Asked Questions (FAQs), please reach out to us

Research Areas

Each Boston Scientific division reviews research requests for a variety of topics pertaining to Boston Scientific products and associated disease states.

We are currently looking for research in the following areas:

Interventional Cardiology/Structural Heart Topics of Interest

TAVR: Acurate

  • Efficacy in Complex Cases, Unique Aortic Anatomies and subpopulations
  • Embolic protection
  • Health Economics Analysis
     

Watchman

  • Imaging
  • Health Economics Data
  • Blood thinner comparative data
  • Subgroup analysis
     

Complex PCI

  • FFR, iFR, DFR usage
  • Health Economics and Efficiency Analysis
     

Stents and Balloons

  • Agent and Synergy applications and sub-population data
     
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Rhythm & Electrophysiology Topics of Interest

ELECTROPHYSIOLOGY: Cardiac Mapping and Ablation

Personalization of Ablation Strategy

  • Atrial fibrillation strategy personalization when considering multiple technology options

Ultrahigh Density Mapping and RF Ablation Catheters

  • Characterization and prospective evaluation of local impedance-guided AF ablation using DIRECTSENSE (INTELLANAV MIFI OI & STABLEPOINT Catheters)
  • DIRECTSENSE workflow and substrate characterization in complex cases
  • High-power short duration ablation workflow for pulmonary vein isolation
  • Procedural best practices and outcomes with state-of-the-art technology, including RHTYTHMIA HDx™ with ultra-high-definition mapping and/or DIRECTSENSE™, AutoTag, and LUMIPOINT™ features
  • Substrate mapping and scar voltage characterization using RHYTHMIA HDx™

PVI with Cryoablation Technologies

  • Optimal dosing strategy for cryoablation using the POLARx cryoballoon
  • Procedural best practices, efficiencies, and long-term clinical outcomes

RHYTHM MANAGEMENT Devices

Heart Failure Diagnostics on CIED Devices

  • Intersection of HeartLogic and arrhythmic events and monitoring (e.g. arrhythmia burden, intervention decision & monitoring of response)
  • Data management and workflow strategies utilizing HeartLogic alerts
  • Treatment protocols for the whole alert cycle and relation to clinical outcomes

Implantable Cardiac Monitor

  • Comparison of data management and clinic burden between LUX-Dx and other monitoring systems
  • Use and performance of novel features including AT algorithm or remote programming
  • User experience including implant and signal quality
  • Patient experience and usefulness of mobile applications

Subcutaneous ICD

  • Best practices to assure long term device efficacy for spontaneous arrhythmias, particularly at device changeout
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Endoscopy Areas of Interest

  • SpyDiscover (Surgical or Percutaneous) 
  • Cholangioscopy and Bil RFA in Occluded Bil SEMS 
  • Biliary RFA focused on improving life expectancy and reducing re-intervention rates
  • Hybrid ESD or Hybrid EMR as a step to ESD using ProKnife
  • Single Use Duodenoscopes 
  • Single Use Bronchoscopes 
  • Clipping for:
    • Anchoring of J-tubes
    • Marking
    • Closure
  • Specific areas of interest in these topics include but are not limited to the following:
    • Economic Data (Reduced procedural time, decreased length of hospital stay, reduced complications, lower hospital)
    • Safety and efficacy
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Urology and Pelvic Health Topics of Interest

Urolithiasis

  • Treatment outcomes in upper tract urinary stone disease
     

BPH

  • Treatment outcomes and QoL in BPH
     

Cancer

  • Spacing and marking for radiation in various anatomies
     

Female Stress Urinary Incontinence

  • The case for minislings as standard of care therapy for stress urinary incontinence
    • Patient experience
    • Economics
  • A systematic review and meta-analysis of the safety and efficacy of urinary slings for treating female stress urinary incontinence
  • Incidence of complications following sling surgery in high risk women (obesity, medical comorbidities, concomitant hysterectomy etc.)
  • Learning curve for Solyx
     

Pelvic Floor Reconstruction

  • Use of Capio in native tissue repair for prolapse
  • Safety and efficacy of Y- mesh implanted by transabdominal route
     

Male Stress Urinary Incontinence

  • AUS / AdVance XP vs comparative device studies
    • Patient and/or Caregiver satisfaction/experience
    • Performance & treatment outcomes
  • Economics of Incontinence
    • Coping costs (i.e. pads/laundry/pills)
    • Economic impact on society
    • Patient productivity
    • Mental health
  • Benefit of diagnosing Incontinence
    • Cardiovascular
    • Diabetes
    • Obesity
  • Female AUS studies


Male Erectile Dysfunction (ED)

  • AMS 700 / Tactra vs other competitive devices
    • Patient and/or Partner satisfaction/experience
    • Performance & treatment outcomes
  • Economics of ED
    • Cost effectiveness of IPP as first line therapy
    • Coping costs (i.e. alternative erectile dysfunction solutions)
    • Economic impact on society
    • Patient productivity
    • Mental health
  • Benefits of diagnosing ED
    • Cardiovascular
    • Diabetes
    • Obesity
 
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Neuromodulation Topics of Interest

  • Spinal Cord Stimulation
    • Treatment of chronic, intractable pain of the back and legs using the Spectra WaveWriter™ SCS System
      • Of particular interest:
        • Efficacy of combination therapy
        • Programming optimization
        • Contour™ field shaping algorithm vs other field shapes
        • Anatomical vs paresthesia-based neural targeting
  • Deep Brain Stimulation
    • Treatment of Parkinson’s Disease and other movement disorders using Vercise™ Deep Brain Stimulation System
      • Of particular interest:
        • Freezing of gait
        • Replacement of other DBS systems with Vercise DBS System
        • Use of multiple frequencies on one lead
        • Use of current fractionalization to maximize overlap with desired structures and minimize stimulation of non-target tissue
        • Novel targets for Parkinson’s Disease, Dystonia, Tremor (may require IDE)

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How the U.S. Physician Payment Sunshine Act Impacts Sponsored Researchers

The U.S. Physician Payment Sunshine Act requires all pharmaceutical, biologic and medical device manufacturers – like Boston Scientific – to report annually to the U.S. government payments and transfers of value made to U.S. physicians and teaching hospitals. This will include educational and research grants and charitable donations. 

Read additional details about the U.S. Physician Payment Sunshine Act

 

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