Rectal Hydrogel Spacer Improves Late Gastrointestinal Toxicity Compared to Rectal Balloon Immobilization After Proton Beam Radiotherapy for Localized Prostate Cancer: A Retrospective Observational Study
By: Dinh TT, Lee HJ, Macomber MW, et al.
From 2013 to 2018, 267 patients with localized, clinical stage T1-4 prostate adenocarcinoma were treated at a single institution using conventionally fractionated, dose-escalated PBT. 192 patients were treated with rectal balloon immobilization and 75 were treated with rectal spacer. Patient-reported GI toxicity was prospectively collected while the incidence of rectal bleeding was retrospectively reviewed from patient records.