Expanding the Utilization of Rectal Spacer Hydrogel for Larger Prostate Glands (>80cc): Feasibility and Dosimetric Outcomes
By: Fagundes M, Rodrigues MA, Olszewski S, et al.
33 patients with localized prostate cancer with glands exceeding 80cc were treated at a single institution using intensity-modulated radiotherapy (IMRT, n=15) and proton therapy (n=18) from 2017 to 2019. 16 patients received conventional fractionation and 17 received hypofractionation. Previous prospective multi-institutional studies only included prostates <80cc.1 The mean separation was 9.9 mm (range, 6.6 – 19.4 mm) for glands measuring >80 to 100 cm3 and 8.8 mm (range, 4.7 – 12.3 mm) for glands >100 cm3. Patients were assessed weekly using common terminology criteria for adverse events (CTCAE).