Illustration of SpaceOAR Hydrogel

Product & Procedure

SpaceOAR™ Hydrogel

How SpaceOAR Hydrogel Works

SpaceOAR Hydrogel is designed to help reduce the radiation dose delivered to the rectum during prostate cancer radiation treatments.

When treating prostate cancer patients with radiation therapy, the goal is to destroy the cancer cells while avoiding damage to the surrounding healthy tissue.

anatomy without spaceoar

Anatomy without SpaceOAR Hydrogel

Due to the close proximity between the rectum and the prostate, radiation therapy can unintentionally cause rectal toxicity.

anatomy with spaceoar

Anatomy with SpaceOAR Hydrogel

The hydrogel spacer is designed to temporarily position the anterior rectal wall away from the prostate.

spaceoar with radiation

SpaceOAR Hydrogel with radiation therapy

SpaceOAR Hydrogel is shown to help reduce the radiation dose planned to be delivered to the rectum during prostate cancer radiotherapy.1

The chemistry of SpaceOAR Hydrogel

labeled anatomy

Peri-rectal implantation

Pre-implant space

Pre-implant space

3-month persistence

3-month persistence

12-month absorption

12-month absorption


 T2-weighted MRI of a SpaceOAR Hydrogel patient

Anatomical Illustration

See how SpaceOAR Hydrogel is placed

Perirectal spacers are recommended as a pre-treatment option within the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)*

Learn how these physicians are implanting SpaceOAR Hydrogel

Dr. Juan Montoya


Urologist Dr. Juan Montoya, President, The Urology Center of Colorado (TUCC), demonstrates the application technique of SpaceOAR Hydrogel.

Dr. Marcio Fagundes


Radiation Oncologist Dr. Marcio Fagundes, Medical Director and Vice Chair, Miami Cancer Institute at Baptist Health South Florida, demonstrates the technique to inject SpaceOAR Hydrogel between the prostate and rectum through a transperineal approach.

physician education

*Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Guideline Name V.2.2020. © National Comprehensive Cancer Network, Inc. 2020. All rights reserved. Accessed July 8, 2020. To view the most recent and complete version of the guideline, go online to


  1. Mariados N, Sylvester J, Shah D, et al. Hydrogel spacer prospective multicenter randomized controlled pivotal trial: dosimetric and clinical effects ofperirectal spacer application in men undergoing prostate image guided intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):971-7.