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The LUX-Dx II+™ Insertable Cardiac Monitor (ICM) System builds upon the first generation LUX-Dx™ ICM System, with enhanced dual-stage algorithms that automatically detect and verify potential arrhythmias before sending for clinic review, providing reliable data and prioritizing actionable alerts.
The Atrial Fibrillation (AF) algorithm uses R-R variability to detect potential AFib rhythms. The verification stage uses several criteria including adaptive morphology, noise discrimination and pattern detectors to identify and reject false positives. New with the LUX-Dx II+ ICM is an additional verification step to reject false positives due to repeating sequential patterns and an update to merge adjacent AFib episodes to reduce the amount of episodes for review.
38%
reduction in AFib false positives while maintaining high relative sensitivity1*
26%
fewer AFib S-ECG episodes for review2*
Learn more about the enhanced dual-stage AF Algorithm on the LUX-Dx II+ ICM.
This dual-stage algorithm uses a patient-specific morphology assessment to detect potential premature ventricular contraction (PVC) sequence types like couplets and triplets. It provides a daily burden percentage with advanced programming and is the only ICM with an actionable PVC Burden alert.**
100%
PPV
when identifying patients with a PVC burden ≥ 10%3†
84%
sensitivity
when identifying patients with a PVC burden ≥ 10%3†
Discover how the PVC Burden dual-stage algorithm identifies PVC sequences and reports daily burden percentages.
This algorithm continues to use R-R intervals to detect pause episodes. The enhanced algorithm includes an additional verification step that further rejects false positives due to a low signal-to-noise ratio. Additionally, the LUX-Dx II+ ICM is the only ICM with advanced nighttime pause programming**—to detect, differentiate and record specified nighttime pause events separately.
57%
fewer pause S-ECG episodes for review2*
49%
reduction in pause false positives4*
Learn more about the LUX-Dx II+ ICM's enhanced dual-stage Pause algorithm and unique nighttime programming.
The algorithm continues to use rate and duration parameters during the detection stage to identify potential Brady episodes. During the verification stage, episodes are further examined and rejected if undersensing is identified. New with the LUX-Dx II+ ICM System is advanced nighttime programming to detect, differentiate and record specified nighttime Brady events separately.
75%
fewer Brady S-ECG episodes for review2*
Explore details of the dual-stage Brady algorithm, including the advanced nighttime programming capabilities.
The Atrial Tachycardia (AT) algorithm uses rate, duration and built-in flexibility to detect either short or long duration AT or atrial flutter based on heart rate and R-R variability. The LUX-Dx ICM Systems are the only ICMs with independent AT and AF programming,** enabling better detection of clinically relevant regular arrhythmias—without compromising ideal AF detection settings.
See how to program the only ICM with an independently programmable AT algorithm.
This algorithm uses traditional implantable cardioverter defibrillator (ICD)-based rate and duration parameters during the detection stage. The verification stage uses a machine-learning-based decision tree to classify Tachy episodes as ventricular tachycardia (VT) or supraventricular tachycardia (SVT), or to reject as noise.
See how the LUX-Dx II+ ICM uses decision trees to classify VT and SVT episodes.
The LUX-Dx II+ ICM System has a proven ability to prioritize clinically relevant events.
Sign up for our email list to stay up to date on the latest LUX-Dx ICM Systems product releases, clinical updates, trainings and more.
Reach out to our team to get more information about the LUX-Dx II+ ICM System.
* Simulated performance tested on real-world LUX-Dx ICM events
** As of 3/3/2025: REVEAL LINQ™ Clinician Manual, LINQ II™ Clinician Manual, BIOMONITOR III™ Technical Manual, BIOMONITOR IIIm™ Technical Manual, BIOMONITOR IV™ Technical Manual, Merlin Patient Care System for SJM Confirm™ ICM, Confirm Rx™ and JOT Dx™ ICM Help Manual, Merlin Patient Care System Assert-IQ™ ICM Help Manual
† In silico testing of algorithm performance on 12-lead Holter data
1 Richards M, Perschbacher D, Mahajan D, Saha S, Herrmann K, Frost K. Novel Algorithm for Improved AF Detection in Insertable Cardiac Monitors. Heart Rhythm. 2022;19(5):S289-S290. doi:10.1016/j.hrthm.2022.03.206
2 Rajan A, Perschbacher D, Mahajan D, et al. Improving Clinic Workflow and Diagnosis for the LUX-Dx Insertable Cardiac Monitor. Heart Rhythm. 2022;19(5):S235. doi:10.1016/j.hroo.2025.01.004
3 Siejko KZ, Kupfer M, Rajan A, Herrmann K, Nair D. Premature ventricular contraction detection and estimation of daily burden by an insertable cardiac monitor. Heart Rhythm O2. 2025. doi:10.1016/j.hroo.2025.01.004
4 Burke MC, Ravikumar V, Siejko K, Bohn D, Verdino RJ. Enhanced pause algorithm for insertable cardiac monitor reduces clinical review burden. Heart Rhythm. 2023;20(5):S723. doi: 10.1016/j.hrttvn.2023.03.1498