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DIRECTSENSE™ Technology Clinical Data

Explore pre-clinical and clinical data supporting the benefits of having localized tissue insights and critical feedback during radiofrequency (RF) ablation procedures.

Pre-Clinical Data

Chart showing the correlation between temperature and local impedance during RF ablation.

Intra-lesion Temperature Rise And Local Impedance Drop Predictive of Lesion Growth on RF Ablation Catheter With Mini Electrodes (Download Poster)
Abstract Accepted to Heart Rhythm Annual Meeting, Garrott, et al., May 2020. Distributed with permission from the Heart Rhythm Society.

Novel Measure of Local Impedance Predicts Catheter-Tissue Contact and Lesion Formation
Circ Arrhythm Electrophysiol, Sulkin, et al., April 2018


Clinical Data

Local Impedance Drop Predicts Durable Conduction Block in Patients With Paroxysmal Atrial Fibrillation
JACC Clin Electrophysiol, García-Bolao I, Ramos P, Luik A, et al. February 2022

Clinical Utility of Local Impedance Monitoring During Pulmonary Vein Isolation
Journal of Cardiovascular Electrophysiology, Masuda, et al., July 2020

Optimal Local Impedance Drops for an Effective Radiofrequency Ablation During Cavo‐Tricuspid Isthmus Ablation
Journal of Arrhythmia, Sasaki, et al., July 2020

A Novel Local Impedance Algorithm to Guide Effective Pulmonary Vein Isolation in Atrial Fibrillation Patients: Preliminary Experience Across Different Ablation Sites from the CHARISMA Pilot Study
Journal of Cardiovascular Electrophysiology, Segreti, et al., July 2020

Local Impedance-Guided Ablation and Ultra-High Density Mapping Provide Improved Ablation Metrics vs Conventional or Contact Force-Guided Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter
Europace, Saraf, et al., June 2020

Pre-ablation Local Impedance is Predictive of Lesion Formation in Patients with Paroxysmal Atrial Fibrillation: Results of the LOCALIZE Clinical Trial
HRS 2020 Science Online, Das, et al., May 2020


Local Impedance Drop During Pulmonary Vein Isolation Predicts Late Reconnection in Patients with Paroxysmal Atrial Fibrillation: Results of the LOCALIZE Clinical Trial (Download Abstract)
HRS 2020 Science Online, García-Bolao, et al., May 2020.  Distributed with permission from the Heart Rhythm Society.

The First Clinical Experiences of the Novel Local Impedance Monitoring (DIRECTSENSE) During Pulmonary Vein Isolation
HRS 2020 Science Online, Tanaka, et al., May 2020

Local Impedance Guides Catheter Ablation in Patients with Ventricular Tachycardia
J Cardiovasc Electrophysiol, Münkler, et al., January 2020

High-Density Mapping-Based Ablation Strategy in a 30-Year-Old Patient with a History of Myocarditis
Europace, Münkler, et al., August 2019

A Novel Assessment of Local Impedance During Catheter Ablation: Initial Experience in Humans Comparing Local and Generator Measurements
Europace, Gunawardene, et al., January 2019

First Clinical Use of Novel Ablation Catheter Incorporating Local Impedance Data
J Cardiovasc Electrophysiol, Martin, et al., September 2018


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