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Two physicians review video image of MANTIS™ Clip closing a defect during an endoscopic submucosal dissection procedure

See how physicians Anchor, Mobilize, Close

Case studies for MANTIS™ Clip

MANTIS Clip (abbreviated as MANTIS) is designed to deliver tissue span and apposition capabilities, enabling a three-step approach to closing large defects (<3cm) and allowing users to Anchor, Mobilize, and Close.1,2,3 Watch the case footage below to see how MANTIS and the proprietary TruGrip™ anchor prongs perform during endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) procedures.

Post-EMR Defect Closure Using the Novel Anchor, Mobilize, Close Approach

Dr. Michael Schafer of Midwest Gastrointestinal Associates Omaha, Nebraska, shows how MANTIS TruGrip™ anchor prongs enable physicians to perform EMR defect closure with a novel three-step approach: Anchor, Mobilize, Close.1,2,3


Request a demo and see how MANTIS is purpose-built for closing large defects (<3cm)³ in the GI tract.

“Button” Defect Closure Using MANTIS

Dr. Yutaka Tomizawa, Associate Professor of Medicine, University of Washington, Seattle, Washington, demonstrates a “button” approach4 – as an alternative to a traditional “zipper” technique – for closing a large (<3cm) defect3 with MANTIS during an ESD procedure.

Familiar Technique for Defect Closure with MANTIS

Dr. Yutaka Tomizawa, discusses how using MANTIS is familiar for nurses and techs to perform defect closure –  close, open, rotate, deploy – during an ESD procedure.

See MANTIS in action

Ready to discover how the novel Anchor, Mobilize, Close approach works for your patients? Complete the form below to request a demo from your rep.


1. Boston Scientific conducted a bench study to gather feedback from 16 paid physicians on the use of commercially representative MANTIS™ Clips on excised porcine stomach model and synthetic tissue model. Data on file. The objective of the study was to evaluate MANTIS Clip’s tissue apposition and mobilization design features as compared against Boston Scientific Resolution™ 360 Clips, and other competitive clips. The bench study was performed with minimal training via some preparation in the ex-vivo model. Bench testing results may not necessarily be indicative of clinical performance.

2. The pre-clinical testing was performed by BSC. Data on file. Sixteen paid physicians used MANTIS with anchor, mobilize and close approach on porcine model. Pre-clinical study may not necessarily be indicative of clinical performance. 

3. Liaquat, H., Rohn, E., & Rex, D. K. Prophylactic clip closure reduced the risk of delayed postpolypectomy hemorrhage: Experience in 277 clipped large sessile or flat colorectal lesions and 247 control lesions. Gastrointestinal Endoscopy, 2013, 77(3): 401–407.

4. Button approach refers to closing the center of a defect first, as opposed to a traditional zipper technique, where a defect is closed from one side to the other.