HeartLogic Clinical Data
Explore the clinical data and real-world evidence showing how HeartLogic Heart Failure Diagnostic changes the future of electrophysiology and allows you to do things you couldn’t do before.
Time Course of HF Decompensation1
Emulating Clinical Assessment via Physiologic Sensor Monitoring
Electrophysiology Insights
Relationship Between Atrial Fibrillation and HeartLogic Index2
HeartLogic May Detect Sub-Optimal BiV Pacing and Poor Physiologic Response3
HeartLogic May Identify Patients Vulnerable to RV Pacing 4
MultiSENSE Study Results5
70% SENSITIVITY
in Detecting Heart Failure Events
A MEDIAN OF 34 DAYS
Advance Notice of Worsening Heart Failure
<2 TOTAL ALERTS
Per Patient Per Year
Real-World Evidence
Real-World Results Compared to Validation Data Set
| MultiSENSE5 (Validation Data Set) |
Capucci et al.2 (ESC HF 2019) |
Santini et al.6 (Clin Card 2020) |
RE-HEART Phase I7 (ESC HF 2020) |
RE-HEART Phase II8 (ESC HF 2020) |
|
|---|---|---|---|---|---|
| SENSITIVITY | 70% | 100%* | 69%* | N/A | N/A |
| UNEXPLAINED ALERT RATE | 1.47 | 0.41 | 0.37 | 0.25 | 0.13 |
Highlights from Real-World Studies
80% OF ALERTS
Provided New Information to Clinicians6
ALERTS PRECEDED HF SYMPTOMS
by a Median of 12 Days2
ALERTS PRECEDED HF EVENTS
by a Median of 38 Days2
Physician Perspectives
HFSA 2019: HeartLogic™ – Validated Evidence, Clinical Implementation and Utility
John P. Boehmer, MD discusses the MultiSENSE study results, implementing the HeartLogic sensors in clinical practice and the MANAGE-HF trial.
Heart Rhythm 2019: HeartLogic – A Multi-Sensor HF Diagnostic
Industry-leading experts discuss clinical evidence and practical considerations for HeartLogic Heart Failure Diagnostic at Heart Rhythm 2019.
AAHFN 2019: HeartLogic – Clinical Evidence and Practical Consideration
Distinguished faculty present data from the MultiSENSE study and talk about integrating HeartLogic into their clinic workflow at AAHFN 2019.
HeartLogic Clinical Compendium
Review a compilation of relevant publication references that form the clinical foundation of the HeartLogic Heart Failure Diagnostic, organized by sensor trend/topic area and relevance.
Stay Up to Date
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Products
Your extraordinary talent. Our extraordinary technology. Explore the Boston Scientific CRT-Ds and ICDs that feature HeartLogic.
LATITUDE NXT™ Remote Patient Management System: Indications, Safety and Warnings
Resonate™ ICD: Indications, Safety and Warnings
Resonate™ CRT-D: Indications, Safety and Warnings
References
1. Adamson PB. Pathophysiology of the transition from chronic compensated and acute decompensated heart failure: new insights from continuous monitoring devices. Curr Heart Fail Rep. 2009 Dec;6(4):287-92. doi: 10.1007/s11897-009-0039-z.
2. Capucci A, Healey JS. Temporal association of atrial fibrillation with device-based heart failure status in patients with CRT. Oral presentation and LBCT presented at: EHRA Congress; March 2019, Lisbon, Portugal.
3. Varma N, Cao M, Schloss EJ, Ahmed R, Stolen C, Boehmer JP. Progressive worsening in device base failure sensors measurements are associated with sub-optimal BiV pacing percentages in CRT-D patients. J Heart Fail. 2019;21(Suppl. S1):370. doi: 10.1002/ejhf.1488
4. Varma N, Stein KM, Thakur PH, Jones PW, Ahmed R, J Boehmer J. Multiparametric analysis of device based physiological sensors may identify ICD patients reacting adversely to right ventricular pacing [abstract]. Heart Rhythm. 2019;16(5):S58-S59.
5. Boehmer JP, Hariharan R, Devecchi FG, et al. A multisensor algorithm predicts heart failure events in patients with implanted devices: results from the MultiSENSE study. JACC Heart Fail. 2017 Mar;5(3):216-25. doi: 10.1016/j.jchf.2016.12.011.
6. Santini L, D’Onofrio A, Russo AD, et al. Prospective evaluation of the multisensor HeartLogic algorithm for heart failure monitoring. Clin Card. 2020;43(7):691-697. doi: 10.1002/clc.23366
7. De Juan Baguda J, Gavira Gomex JJ, Pachó Iglesias M, et al. Preliminary results of the Spanish multicentric HeartLogic (RE-HEART) registry: a blinded analysis. Abstract presented virtually at: ESC-HFA Congress 2020.
8. De Juan Baguda J, Gavira Gomex JJ, Pachó Iglesias M, et al. Preliminary results of the Spanish multicentric HeartLogic (RE-HEART) registry: adoption of an alert-based heart failure management approach. Abstract presented virtually at: ESC-HFA Congress 2020.
*The HeartLogic Index and Alert were validated using data from the MultiSENSE study; however, HeartLogic’s impact on clinical outcome has not been established. Establishment of the impact will require a post market trial designed specifically to study clinical outcomes directly related to the use of this feature.