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Deep Brain Stimulation (DBS) device support

How Deep Brain Stimulation works

How Deep Brain Stimulation works

Model of a skeleton with Boston Scientific’s DBS device implanted

People living with Parkinson’s Disease (PD) or essential tremor (ET) experience a disturbance in motor symptoms because of low dopamine levels in the brain causing abnormal signaling. DBS can help regulate those signals through electrical stimulation. As a result, symptoms are often reduced.1


Your doctor will place one or two insulated wires called “leads” in the brain, which connect to a thin wire called an “extension.” 

Two leads lying next to each other


A small device called a “stimulator” is implanted under the skin in the chest, which also connects to the extension. 

Vercise Genus R-16


The stimulator sends mild electrical pulses through the extensions and leads to specific regions of the brain. 

Mild electrical pulses


Your device is programmed with Image Guided Programming; a technology that allows your physician to see exactly where your leads are placed and exactly where the therapy is being delivered. 

Image guided programming

Benefits of DBS

DBS has changed the lives of people with PD, easing symptoms and returning function that was once lost. The results of DBS vary from person to person depending on the overall level of health, progression, and window of implementation. 

Benefits of DBS include

  • DBS is a safe and effective solution to manage and reduce symptoms such as: tremor, slowness, rigidity, uncontrolled movements, incontinence, and moodiness
  • Your initial programming session may be 20 minutes shorter than a typical programming session with Image Guided Programming²
  • For Parkinson’s Disease (PD) patients:
    • May allow for a reduction in number of medications taken³
    • Provide 6 hours of more “On Time”, giving you control and independence to live your life free of rigidity, freezing or the troublesome dyskinesia sometimes caused by medications⁴
    • Patients with tremor experienced an average of 70% reduction of symptoms, depending on type and location⁵
    • Patients showed marked improvements in minor functions and sustained improvement for at least 5 years⁶
  • For Essential Tremor (ET) patients:
    • According to research, patients exhibit 60-90% improvement of tremor⁷  
    • 98% of patients receiving DBS therapy for Essential Tremor would recommend it to others⁸
Older man lifting weights in gym

Know the timing of DBS

There is an ideal “window” for people with PD to consider DBS surgery. In general, it’s best to consider DBS when you’re still responding to levodopa, but you’re no longer able to control your motor symptoms with medication alone. This timing will differ from patient to patient, as the path and progression of Parkinson’s is personal. Talk to your doctor in the early stages of treatment, and voice your desire to explore alternatives like DBS as you move through your journey.5


Happy couple smiling and embracing

“Thanks to DBS, my husband Kenny has experienced a drastic improvement in his symptoms and reduction in his medicine. That was a huge relief.”

- Tania—Caregiver to Kenny, a Boston Scientific DBS patient*

When DBS is most effective⁶

Remember, PD varies from person to person. 

Icon of a man walking


There is no age cut-off for DBS, yet overall health status will influence if you are a good candidate or not.

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You are still responding positively to Parkinson’s Disease medications (levodopa) but are no longer able to control motor symptoms with only medications.

Icon of a magnifying glass


Signs and evidence of dementia may influence if a specialist recommends you for DBS.

The best way to control any disease progression is to be proactive and start talking to your care team now. A DBS specialist could help you.

We’re here to help

Our patient services team is here to support you throughout your DBS journey.

Available 5 am to 5 pm PT, Monday through Friday 

*The patient quotes in this material describe real personal experiences. Individual results may vary. Consult with your physician to determine if you are a candidate for this procedure and what you may gain from therapy. 


  1. Parkinson’s Foundation. Causes. Accessed July 1, 2021.
  2. Lange F, Steigerwald F, Malzacher T, Brandt GA, Odorfer TM, Roothans J, Reich MM, Fricke P, Volkmann J, Matthies C and Capetian PD (2021) Reduced Programming Time and Strong Symptom Control Even in Chronic Course Through Imaging-Based DBS Programming. Front. Neurol. 12:785529. doi: 10.3389/fneur.2021.785529
  3. Timmermann L, Jain R, Chen L, et al. Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson’s disease (the VANTAGE study): a non-randomised, prospective, multicentre, open-label study. Lancet Neurol. 2015;14:693-701. doi: 10.1016/S1474-4422(15)00087-3
  4. Vitek JL, Jain R, Chen L, et al. Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson’s disease (INTREPID): a multicenter, double-blind, randomised, sham-controlled study. Lancet Neurology. 2020;19(6):491‐501. doi:10.1016/S1474-4422(20)30108-3
  5. Farris SM, Giroux, ML. (2013). DBS: A Patient Guide to Deep Brain Stimulation. 1st ed. CreateSpace Independent Publishing Platform; 2013.
  6. Krack P, Batir A, Van Blercom, N. Five-year follow-up of bilateral stimulation of the subthalmic nucleus in advanced Parkinson’s disease. N Eng J Med. 2003:349(20):1925-1934. doi:10.1056/NEJMoa035275
  7. Zesiewicz T, Chari A, Jahan I, Miller AM, Sullivan KL. Overview of essential tremor. Neuropsychiatr Dis Treat. 2010;6(1):401-408,
  8. R.E. Wharen Jr., et al., Thalamic DBS with a constant-current device in essential tremor: A controlled clinical trial, Parkinsonism and Related Disorders (2017),
MRI conditional symbol.

The Vercise Genus™ DBS System, Vercise Genus Mixed System with M8 Adapter, Vercise Gevia™ DBS System, and Vercise™ DBS Lead-only system (before Stimulator is implanted) provide safe access to full-body MRI scans when used with specific components and the patient is exposed to the MRI environment under specific conditions defined in the supplemental manual ImageReady™ MRI Guidelines for Boston Scientific DBS Systems.

US Indication for Use: The Boston Scientific Vercise™ PC, Vercise Gevia™, Vercise Genus™ Deep Brain Stimulation Systems are indicated for use in:

  • Bilateral stimulation of the subthalamic nucleus (STN) as an adjunctive therapy in reducing some of the symptoms of moderate to advanced levodopa-responsive Parkinson’s disease (PD) that are not adequately controlled with medication.
  • Bilateral stimulation of the internal globus pallidus (GPi) as an adjunctive therapy in reducing some of the symptoms of advanced levodopa-responsive Parkinson’s disease (PD) that are not adequately controlled with medication.
  • Unilateral thalamic stimulation of the ventral intermediate nucleus (VIM) is indicated for the suppression of tremor in the upper extremity. The system is intended for use in patients who are diagnosed with essential tremor or parkinsonian tremor not adequately controlled by medications and where the tremor constitutes a significant functional disability. 
  • The Boston Scientific Vercise Deep Brain Stimulation System is indicated for use in:
  • Bilateral stimulation of the subthalamic nucleus (STN) as an adjunctive therapy in reducing some of the symptoms of moderate to advanced levodopa-responsive Parkinson’s disease (PD) that are not adequately controlled with medication.

Contraindications: The Boston Scientific Deep Brain Stimulation (DBS) Systems are not recommended for patients who will be exposed to the following procedures: Diathermy as either a treatment for a medical condition or as part of a surgical procedure, Electroconvulsive Therapy (ECT) and Transcranial Magnetic Stimulation (TMS).  The safety of these therapies in patients implanted with the Boston Scientific DBS System has not been established.  Patients implanted with Boston Scientific DBS Systems without ImageReady™ MRI Technology should not be exposed to Magnetic Resonance Imaging (MRI). Patients implanted with the Vercise Gevia or Vercise Genus or Vercise Genus Mixed System with M8 Adapter or Vercise DBS Lead-Only System (before Stimulator is implanted) with ImageReady MRI Technology are Full Body MR Conditional only when exposed to the MRI environment under the specific conditions defined in ImageReady MRI Guidelines for Boston Scientific DBS Systems.  Boston Scientific DBS Systems are not recommended for patients who are unable to operate the system or are poor surgical candidates or who experience unsuccessful test stimulation. 

Warnings: Unauthorized modification to the medical devices is prohibited.  You should not be exposed to high stimulation levels.  High level of stimulation may damage brain tissue.  Patients implanted with a Boston Scientific DBS System may be at risk for intracranial hemorrhages (bleeding in the brain) during DBS lead placement.   Strong electromagnetic fields, such as power generators, security screeners or theft detection systems, can potentially turn the stimulator off, or cause unpredictable changes in stimulation. The system should not be charged while sleeping.  If you notice new onset or worsening depression, changes in mood or behavior or impulse control, or have thoughts of suicide contact your physician or emergency services immediately.  Chemical burns may result if the Stimulator housing is ruptured or pierced.  The Boston Scientific DBS Systems may interfere with the operation of implanted stimulation devices, such as cardiac pacemakers, implanted cardioverter defibrillators, or medication delivery pumps. Patients should operate motorized vehicles or potentially dangerous machinery with caution.  It is unknown if the device may hurt an unborn baby. Your doctor may be able to provide additional information on the Boston Scientific DBS Systems.  For complete indications for use, contraindications, warnings, precautions, and side effects, see or call 833-DBS-INFO or 833-327-4636

Caution: U.S. Federal law restricts this device to sale by or on the order of a physician.