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EKOS™ Endovascular System


OPTALYSE long-term data

Sustained RV remodeling & improved patient outcomes

In the OPTALYSE study which evaluated the optimal dose/duration of EKOS treatment, patients were followed for one year. In addition to showing quick improvement in RV function, the long-term data showed sustained RV remodeling out to one-year. OPTALYSE was also the first study of an interventional pulmonary embolism (PE) treatment to show improvement in patient quality of life outcomes.1


RV function

RV/LV ratio continued to reduce after 48h

p value <030001@365d

Graph of RV/LV reduction after 48 hours


Mean 6-minute walk test distance

Graph of 6-minute walk test to measure endurance over 1 year

Physical functioning

Mean PROMUS-PF-6b scores

Graph of PROMUS-PF-6b scores for physical functioning over 1 year

Quality of life

Mean PEmb-QOL scores

 Graph of Pemb-QOL scores for quality of life over 1 year
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1. Tapson V et al. A randomized trial of the optimum duration of acoustic pulse thrombolysis procedure in acute intermediate-risk pulmonary embolism.  JACC: Cardiovascular Interventions 2018; 11(14):1401-1410.