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TheraSphere Y-90 Glass Microsphere glowing against blue background.

TheraSphere™ Y-90 Glass Microspheres

Control for durable outcomes

TheraSphere is a targeted radioembolization therapy made of glass microspheres containing radioactive Yttrium-90 (Y-90). Designed for control to achieve durable patient outcomes, TheraSphere preserves quality of life and provides reproducible results for treating and referring physicians. As the only FDA-approved Y-90 therapy for HCC, it is a cost-effective procedure backed by committed support from the industry leader, Boston Scientific.

Durability leads to quality of life

Confidently destroy tumor cells with proven ablative dosing and a good patient safety profile.1


Get started with TheraSphere

Order TheraSphere using TheraSphere Now, a cloud-based website that facilitates personalized treatment order submission, tracking and order management. Increase treatment flexibility with expedited delivery of ready-to-deploy doses.


Find coding and economic resources for health care practitioners and their partners.


  1. LEGACY: Salem R, Johnson GE, Kim E, Riaz A, Bishay V, Boucher E, Fowers K, Lewandowski R, Padia SA. Yttrium-90 Radioembolization for the Treatment of Solitary, Unresectable Hepatocellular Carcinoma: The LEGACY Study. Hepatology. 2021 Mar 19. doi: 10.1002/hep.31819. Percentage shown reflects patients who were eligible for tumor response assessment.
  2. Pasciak, A. S., Abiola, G., Liddell, R. P., Crookston, N., Besharati, S., Donahue, D., Thompson, R. E., Frey, E., Anders, R. A., Dreher, M. R., & Weiss, C. R. (2019). The number of microspheres in Y-90 radioembolization directly affects normal tissue radiation exposure. European Journal of Nuclear Medicine and Molecular Imaging, 47(4), 816–827.

*Refers to HCC or associated tumors .