SYNTAX II: Utilizing contemporary PCI tools and Techniques produces CABG-like outcomes

The SYNTAX II Trial evaluated patients with three-vessel disease; the PCI treatment algorithm included updated techniques and technologies: Physiological Assessment, IVUS Guidance, Complete Revascularization Techniques and Contemporary Technology- including the SYNERGY™ BP Stent*.

Four Pillars
*The safety and effectiveness of the SYNERGY Stent has not been established in patients with three-vessel disease or chronic total occlusions.


Physiological Assessment

Physiologic assessment occurred in 98% of patients that contributed to:

IVUS Guidance

IVUS-guided treatment is a core tenant of the updated PCI treatment algorithm. IVUS-guided stent optimization contributed to reduced adverse events.

Current Revascularization Techniques

The contemporary PCI algorithm, including the hybrid algorithm, demonstrated a significantly higher procedural success rate.

Contemporary Technology

Together contemporary techniques and technologies support that PCI could be an option for patients with complex three-vessel disease.

Low rates of revascularization, peri-procedural MI and acute ST suggest that contemporary technologies might help in reducing procedural related complications.


The SYNTAX II Trial utilizing SYNERGY™ BP-DES, physiological assessment, IVUS guidance, and contemporary state-of-the-art PCI techniques demonstrated equivalent outcomes to CABG in patients with three-vessel disease at 3-years.1†

SYNTAX II Case Presentation By Simon Walsh, VIdeo
SYNTAX II Functional Assessment in Multivessel Disease by Javier Escaned, VIdeo
SYNTAX II How Imaging May Improve the Outcomes in Patients by Adrian Banning, VIdeo
SYNTAX II Rotational Atherectomy for Calcified Lesion Preparation by Gert Richardt, VIdeo
SYNTAX II Rationale and Tee Up by Javier Escaned, VIdeo
SYNTAX II 3-year Results by Patrick W Serruys, VIdeo

SYNTAX II Vignette,Powerpoint