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Clinical Performance

Clinically Proven Clip

A robust clinical and economical track record backed by over 400 cinical articles.


In a global prospective multi-center randomized controlled study comparing polypectomy without clipping to prophylactic clipping, results showed clipping significantly reduced post-procedure bleeding from 7.1% to 3.5%.1
Bleeding risk comparison graph
In the clip group, only Resolution and Resolution 360 clips were used.
Non-pedunculated colorectal polyps > 20 mm
N=919 patients randomized with complete follow up; N=455 clip group and N=464 control group (no-clip)
The Resolution™ Clip and Resolution 360™ Clip are indicated for Hemostasis for: Mucosal/sub-mucosal defects <3cm. This study concludes that the defects that were closed were greater than or equal to 2cm. Most that were closed were between 2cm and 4cm, which means some of which were clipped may have been off label. Boston Scientific does not promote use of product off label.
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The Resolution™ portfolio has robust clinical support — citen in more than 400 published studies.

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In a bench study evaluating multiple commercially available TTS clips, Resolution 360 showed 100% deployment success on a 10mm thick homogenous compression gel, as compared to a combined 80% failure for Micro-Tech SureClip® and CONMED DuraClip™2
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In a randomized prospective study on hemoclipping of chronic canine ulcers, "the Resolution Clip was retained significantly longer" than other hemoclips in the study with no delay in ulcer healing. Media clip retention was 8 weeks for Resolution Clip compared to 1 and 2 weeks for competitive clips.3
The results of this canine study may not be representative of performance in humans. This study is applicable to Resolution Clip and Resolution 360 Clip.

1. Pohl H, Grimm IS, Moyer MT, et al. Clip Closure Prevents Bleeding After Endoscopic Resection of Large Colon Polyps in a Randomized Trial. Gastroenterology. 2019;157(4):977-984.e3. doi:10.1053/j.gastro.2019.03.019

2. Wang TJ, Aihara H, Thompson AC, Schulman AR, Thompson CC, Ryou M. Choosing the right through-the-scope clip: a rigorous comparison of rotatability, whip, open/close precision, and closure strength (with videos). Gastrointest Endosc. 2019;89(1):77-86.e1.doi:10.1016/j.gie.2018.07.025

3. Jensen DM, Machicado GA, Hirabayashi K. Randomized controlled study of 3 different types of hemoclips for hemostasis of bleeding canine acute gastric ulcers. Gastrointest Endosc. 2006;64(5):768-773. doi:10.1016/j.gie.2006.06.031