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Boston Scientific LUX-Dx II+ Insertable Cardiac Monitor with the words "detect" and "verify."

Dual-stage algorithms

Focused on more actionable alerts

The LUX-Dx II+™ Insertable Cardiac Monitoring (ICM) System uses an enhanced suite of dual-stage algorithms that automatically detect and verify data before sending results, letting you spend your time evaluating actionable alerts with reliable data.


Enhanced atrial fibrillation algorithm 

The AF algorithm uses R-R variability to detect potential AF rhythms. The verification stage uses several criteria including adaptive morphology, noise discrimination and pattern detectors to identify and reject false positives. New with the LUX-Dx II+ ICM is an additional verification step to identify sequential heart rate patterns and an update to merge adjacent AF episodes.

38% reduction in AF false positives while maintaining high relative sensitivity
26% fewer AF S-ECG episodes for review

Enhanced atrial fibrillation algorithm


Novel PVC burden algorithm with programmable alert

This algorithm uses a patient-specific morphology assessment to detect potential premature ventricular contraction (PVC) sequence types like couplets and triplets. It provides a daily burden percentage with advanced programming and is the only ICM with an actionable PVC Burden alert.*

85.4% PPV in detecting singlet, couplet and triplet PVC

Novel PVC algorithm


Enhanced pause algorithm

This algorithm continues to use R-R intervals to detect pause episodes. The enhanced verification step further rejects false positives due to a low Signal-to-Noise Ratio. Additionally, the LUX-Dx II+ ICM is the only ICM with advanced nighttime pause programming*—to detect, differentiate and record specified nighttime pause events separately.

49% reduction in pause false positives
57% fewer nighttime pause S-ECG episodes for review

Enhanced pause algorithm


Enhanced bradycardia algorithm

The algorithm continues to use rate and duration parameters during the detection stage to identify potential brady episodes. During the verification stage, episodes are further examined and rejected if undersensing is identified. New with the LUX-Dx II+ ICM is advanced nighttime programming to detect, differentiate and record specified nighttime Brady events separately. 

75% fewer nighttime Brady S-ECG episodes for review

Enhanced brady algorithm


Atrial tachycardia algorithm

The AT algorithm uses rate, duration and built-in flexibility to detect either short or long duration AT or Atrial Flutter based on heart rate and R-R variability. The LUX-Dx II+ ICM System is the only ICM with independent AT and AF programming,* enabling better detection of clinically relevant regular arrhythmias—without compromising ideal AF detection settings. 

Atrial Tachycardia algorithm


Tachycardia algorithm

This algorithm uses traditional ICD-based rate and duration parameters during the detection stage. The verification stage uses a machine-learning-based decision tree to classify Tachy episodes as VT, SVT or to reject as noise.

Tachycardia algorithm


Demonstrated clinical algorithm performance

The LUX-Dx II+ ICM System has a proven ability to prioritize clinically relevant events.

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References:

1. Richards M, Frost K, Mahajan D, Saha S, Herrmann K, Perschbacher D. Novel Run-Test Algorithm for Improved AF Detection in Insertable Cardiac Monitors. Poster presented at 2022 Heart Rhythm Society; April 2022; San Francisco, CA

2. Rajan A, Perschbacher D, Mahajan D, et al. Improving Clinic Workflow and Diagnosis for the LUX-Dx Insertable Cardiac Monitor. Poster Presented at Heart Rhythm Society; April 2022; San Francisco, CA

3. Burke M, Ravikumar V, Siejko K, Bohn D, Verdino R. Enhanced Pause Algorithm for Insertable Cardiac Monitor Reduces Clinical Review Burden. Poster presented at 2023 Heart Rhythm Society; May 2023; New Orleans, LA

4. Nair D, Herrmann K, Mahajan D, Siejko K. Novel PVC burden algorithm for Insertable Cardiac Monitors (ICMs) detects all PVC sequence types. Poster presented at: 2021 Heart Rhythm Society; July 2021; Boston, MA.

†Simulated performance tested on real-world LUX-Dx ICM events

*As of 7.20.23: REVEAL LINQ™ Clinician Manual, LINQ II™ Clinician Manual, BIOMONITOR III™ Technical Manual, BIOMONITOR IIIm™ Technical Manual, BIOMONITOR IV™ Technical Manual, Merlin Patient Care System for SJM Confirm™ ICM, Confirm Rx™ ICM and Jot Dx™ ICM Help Manual, Merlin Patient Care System Assert-IQ™ ICM Help Manual. All trademarks are the property of their respective owners.