SYNTAX II: Utilizing contemporary PCI tools and Techniques produces CABG-like outcomes

The SYNTAX II Trial evaluated patients with three-vessel disease; the PCI treatment algorithm included updated techniques and technologies: Physiological Assessment, IVUS Guidance, Complete Revascularization Techniques and Contemporary Technology- including the SYNERGY™ BP Stent*.

^{*The safety and effectiveness of the SYNERGY Stent has not been established in patients with three-vessel disease or chronic total occlusions.}

Physiological Assessment

Physiologic assessment occurred in 98% of patients that contributed to:

46 percent reduction of three-vessel disease diagnosis compared to when no physiology was used

IVUS Guidance

IVUS-guided treatment is a core tenant of the updated PCI treatment algorithm. IVUS-guided stent optimization contributed to reduced adverse events.

Current Revascularization Techniques

The contemporary PCI algorithm, including the hybrid algorithm, demonstrated a significantly higher procedural success rate.

Success rates dramatically increased to 87 percent

Contemporary Technology

Together contemporary techniques and technologies support that PCI could be an option for patients with complex three-vessel disease.

Low rates of revascularization, peri-procedural MI and acute ST suggest that contemporary technologies might help in reducing procedural related complications.

The SYNTAX II Trial utilizing SYNERGY™ BP-DES, physiological assessment, IVUS guidance, and contemporary state-of-the-art PCI techniques demonstrated equivalent outcomes to CABG in patients with three-vessel disease at 3-years.^1†

SYNTAX II Trial 3-Year Results Presentations

SYNTAX II Case Presentation By Simon Walsh

“See how utilizing new technologies such as the COMET FFR wire, Opticross HD IVUS catheter, SYNERGY Stent, ROTAPRO Atherectomy System, and JUDO Guidewires through a SYNTAX II approach to a complex case can result in optimal outcomes, leading to long term successful results.”

SYNTAX II Functional Assessment in Multivessel Disease by Javier Escaned

“Physiological assessment of borderline lesions allows for optimal treatment of every patient. See how usage has improved outcomes and why we should be leveraging this therapy in our everyday practices.”

SYNTAX II How Imaging May Improve the Outcomes in Patients by Adrian Banning

“IVUS usage helps physicians understand lesion morphology, leading to the best clinical treatment. SYNTAX II demonstrates higher usage patterns and how that can lead to improved long-term results.”

SYNTAX II Rotational Atherectomy for Calcified Lesion Preparation by Gert Richardt

“Calcium can make treating lesions extremely difficult. Understand how to leverage the ROTAPRO Rotational Atherectomy System to combat this lesion type and how it will not only improve your patients outcomes, but speed up your case.”

SYNTAX II Rationale and Tee Up by Javier Escaned

“SYNTAX II is an all encompassing trial analyzing patient outcomes through utilizing modern techniques and technologies. Understand why this trial was started and how it can impact a physician’s practice.”

SYNTAX II 3-year Results by Patrick W Serruys

“The 3-years results of SYNTAX II, demonstrating CABG-like outcomes through appropriate PCI with the SYNERGY stent, is explained.”

SYNTAX II Vignette

“Understanding the SYNTAX II data is only the beginning. See how the data is applied in a case-based format through this short presentation.”

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