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Closure portfolio

Confidence across the closure continuum

Advancing endoscopic closure through education, expertise, and a comprehensive portfolio

Advancing endoscopic closure through education, expertise, and a comprehensive portfolio

Whether you're looking at a simple defect or a complex one, your goal is the same: a quality closure that minimizes complications. With a comprehensive portfolio of solutions, Boston Scientific offers the closure options you need paired with ongoing rep support and educational opportunities – so you can close with confidence. 

50+

physician education programs annually in endoluminal surgery (ELS) and endoscopic closure 

500+

peer-reviewed clinical articles published referencing OverStitch

Designed for reliability

MANTIS and X-Tack are designed to enable reliable closure in large defects

Closure decision-making, simplified

As closure options expand, choosing the right closure technique is even more important. See why a streamlined set of surgical principles can help.

Guiding principles for closure

Dr. Brian Dunkin explains five key considerations that can guide your selection of a closure technique.


From principles to real-world decisions

Every defect is different. Yet the way you approach each defect doesn't have to be complicated. 

Answer the following question, and we'll show you how the principles Dr. Dunkin explained apply across common closure scenarios. 

What types of defects and procedures are you currently most interested in? 

Closure options

If your practice typically closes routine defects, you're probably familiar with Resolution Clip – a go-to clip for hemostasis and closure. Another option for closing with confidence: MANTIS Clip.

Explore how MANTIS Clip is purpose-built for closing large defects1 and designed for procedural efficiency2. MANTIS is designed to offer both tissue mobilization and closure, an alternative to zipper methods of closure using conventional clips3.

See MANTIS up close

Hear from an expert

If you've been using MANTIS Clip, you know it can close many defects. But how do you manage closure post-resection for procedures such as ESD, POEM, or full-thickness resection?

Instead of relying on through-the-scope (TTS) clips or MANTIS Clip, you could consider using the X-Tack Endoscopic HeliX Tacking System – offering HeliX Tacks tethered with a polypropylene suture. X-Tack allows for independent, TTS placement of fixation points to help address the challenge of spanning defects.

See X-Tack in action

X-Tack vs. MANTIS decision

With MANTIS Clip and X-Tack Endoscopic HeliX Tacking System, you can treat many advanced defects. But for full-thickness defections, you may need more control.

The OverStitch Endoscopic Suturing System enables physicians to access a wide range of gastrointestinal anatomy and deliver reliable full-thickness suturing regardless of anatomy site or treatment type, empowering them to perform more advanced endoluminal procedures and close with confidence.4

See OverStitch work in full thickness

Discover the purse-string suture

Watch Dr. Thompson suture esophageal fistulas

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Expand your closure skills

Visit EDUCARE for comprehensive educational resources.

1. Boston Scientific conducted a bench study to gather feedback from 16 paid physicians on the use of commercially representative MANTIS Clips on excised porcine stomach model and synthetic tissue model. Data on file. The objective of the study was to evaluate MANTIS Clip's tissue apposition and mobilization design features as compared with Boston Scientific Resolution 360 Clips and other competitive clips. The bench study was performed with minimal training via some preparation in the ex-vivo model. Bench testing results may not necessarily be indicative of clinical performance.

2. The pre-clinical testing was performed by BSC. Data on file. Sixteen paid physicians used MANTIS with Anchor, Mobilize, Close approach on porcine model. Pre-clinical study may not necessarily be indicative of clinical performance.

3. The testing was performed by BSC. Data on file. Bench testing results may not necessarily be indicative of clinical performance.

4. R Maselli et al. Endoscopic suturing for GI applications: initial results from a prospective multicenter European registry. Gastrointestinal Endoscopy, 2022; 96, 780-786.

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All photographs taken by Boston Scientific.

CAUTION: U.S. Federal law restricts this device to sale by or on the order of a physician.


Indications, contraindications, warnings, and instructions for use can be found in the product labeling supplied with each device or at IFU-BSCI.com,