Clinical Data
See the data behind FFR, DFR and Pd/Pa

A PCI Guidance portfolio backed by data you can trust

  • Overview on coronary physiology.
  • FFR calculates Pd/Pa during maximal hyperemia.
  • DFR™ calculates a diastolic portion of the cardiac cycle at rest.
  • Pd/Pa calculates the entire cardiac cycle at rest.


Study Methodology & Analysis

  • DFR values were compared to iFR values using the 893 waveform tracings from the 833 patients pooled from the VERIFY 2 and CONTRAST studies
  • The DFR window uses two criteria: Pa < mean Pa and down-sloping Pa
  • No ECG signal were required
  • No need to identify dicrotic notch


Intermediate Lesion1

DFR: 0.90 | iFR: 0.90
Intermediate Lesion

Severe Lesion1

DFR: 0.71 | iFR: 0.71
Severe Lesion


VERIFY 2 + CONTRAST Pooled Analysis: DFR Showed Equivalency to iFR

VERIFY 2 + CONTRAST Pooled Analysis: DFR Showed Equivalency to iFR

VERIFY 2 Analysis: DFR is within the Intra-iFR Variation of ~0.01

Two iFR Measurements Taken Directly After Each Other

  • Greater divergence of the curves demonstrates better prognostic ability
  • There was no statistically significant difference in prognostic performance among any of the NHPRs


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