Clinical Data
See the data behind FFR, DFR and Pd/Pa

A PCI Guidance portfolio backed by data you can trust

Physiology Data Drives Successful, State-of-the-Art PCI

No two CAD patients are the same. SYNTAX II -- which now shows that more PCI patients can experience CABG-like outcomes out to five years -- emphasizes comprehensive physiology assessment before and after intervention. This functional patient information can impact treatment decisions and preparation, as well as provide clinical value post-procedure.


  • Physiologic assessment occurred in 98% of patients. 
  • 1.4 less lesions per patient treated. 
  • Changed three-vessel disease diagnoses in nearly 2/3 of patients.
  • 46% reduction of the three-vessel ischemic disease diagnosis compared to when no physiology was used.
  • FFR-guided stenting reduced rate of composite endpoint of death, nonfatal myocardial infarction, and repeat revascularization (13.2% vs 18.3%). 
  • Patients with ischemic lesions treated by PCI and medical therpy, versus medical therpy alone, had significantly lower rates of death, myocardial infraction, and urgent revascularization.
FFR Provides

The DEFINE trial3 highlights the importance of physiology assessment after PCI. It demonstrates that patients whose baseline ischemia was more effectively treated had significantly improved outcomes and less recurrent angina at one-year post-procedure. Ischemia was measured immediately after intervention via instantaneous wave-free ratio (iFR).

  • Overview on coronary physiology.
  • FFR calculates Pd/Pa during maximal hyperemia.
  • DFR™ calculates a diastolic portion of the cardiac cycle at rest.
  • Pd/Pa calculates the entire cardiac cycle at rest.














No Hyperemic Agent Required


Inclusion in Appropriate Use Criteria*

Workhorse Pressure Guidewire Available


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