PULMONARY EMBOLISM
DISEASE OVERVIEW
CIRCLE STRATEGY
ESC GUIDELINES
CLINICAL DATA
PULMONARY EMBOLISM
DISEASE OVERVIEW
CIRCLE STRATEGY
ESC GUIDELINES
CLINICAL DATA

 
Vascular Surgery / Venous Thromboembolism / Pulmonary Embolism / Clinical Data

 

Hi-PEITHO Trial

 

 

HI-PEITHO is a multi-center, prospective, randomized, controlled trial in the U.S. and Europe that will compare the outcomes of ultrasound-facilitated, catheter-directed, thrombolysis plus anticoagulation vs. anticoagulation alone for the treatment of acute, intermediate-high risk pulmonary embolism (PE)

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The ULTIMA Trial

 

 

Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis
for Acute Intermediate-Risk Pulmonary Embolism
Nils Kucher, MD et al. Circulation 2014; 129: 479-486

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SEATTLE II Trial

 

 

A Prospective, Single-Arm, Multicentre Trial of Ultrasound-Facilitated, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism
G. Piazza MD, MS et al, JACC Cardiovasc Interv. 2015 Aug 24; 8(10): 1382-92

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OPTALYSE PE Study

 

 

Optimum Duration and Dose of tPA with the Acoustic Pulse Thrombolysis Procedure for Submassive Pulmonary Embolism: OPTALYSE PE
Tapson, Victor, et al., “A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial.” JACC: Cardiovascular Interventions Jul 2018, 11 (14) 1401-10

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Nykamp & Laurich Study

 

 

Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Lytic Therapy in Acute Pulmonary Embolism With and Without Haemodynamic Instability
Nykamp M et al. J Vasc Surg: Venous and Lymphatic Disorders 2015: 3(5) 251-7

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