Drug-Coated Balloon

Enhanced Coating Integrity

  • Balanced hydrophobic and hydrophilic properties of TransPaxTM coating, ensures DCB reaches the lesions with the optimal amount of drug for your patient.
  • Fewer particulates are lost distally during the procedure3

Minimise Systemic Loss

AGENT™ Drug-Coated Balloon generates significant fewer drug particulates lost downstream than showed competitors3.
Agent DCB by Boston Scientific generates less downstream material than SeQuent™ Please, In.Pact™ Falcon and Pantera™ Lux
All particulates from insertion, delivery, inflation/deflation, and withdrawal captured on 5 µm filter. In this study, DCBs are delivered in the coronary track model with fluid recirculation. Particulates lost downstream are collected with a Polycarbonate filter and shown here as green dots3.

Coating Transfer

Coating durability is one of the most important factors of a drug coating. If the coating is not durable, there is risk that drug will come off the balloon during the track to the lesion4. Our excipient, acetyl tributyl citrate - ATBC, has a balance of hydrophilic and hydrophobic properties which maintains coating integrity and optimises adhesion to the balloon2 but also allows the coating to transfer to the vessel wall from the balloon during inflation1. The presence of an excipient is critical to achieve desired tissue levels as the excipient modulates the release of the drug.
Difference in durability between TransPax coating and IMDT N.PACT Coating