8th Issue – December 2025
This edition highlights new evidence on the LUX-Dx™ Insertable Cardiac Monitor (ICM), ICD and CRT-D battery longevity, and the S-ICD system. Real-world data demonstrate how LUX-Dx remote reprogramming can streamline monitoring and reduce clinical workload. Recent analyses also confirm notable differences in battery performance across manufacturers, reinforcing the value of devices with longer longevity. Additionally, findings from the HONEST registry provide reassuring outcomes when omitting routine defibrillation testing during S-ICD implantation, supporting a more individualised approach.
7th Issue – September 2025
This edition explores real-world data and clinical trial insights on S-ICD. New findings confirm its safety during physical activity, comparable quality of life to TV-ICDs, and a lower rate of long-term complications. The issue also features key updates on HeartLogic, including its value in reducing 90-day readmission risk and improving resource allocation in heart failure care.
6th Issue – July 2025
This update presents new data on inappropriate shock rates across ICD systems. The EMBLEM™ S-ICD System shows significantly lower rates—seven times fewer than substernal ICDs—while maintaining comparable performance to transvenous systems. These findings reinforce the value of S-ICD in reducing risk and improving patient outcomes.
5th Issue – March 2025
This Clinical Evidence edition reviews CIED remote monitoring trends, Heart Connect's effectiveness, and a PRAETORIAN sub-analysis showing similar inappropriate therapy rates for S-ICD and TV-ICD, though recent S-ICD advancements may impact findings.
4th Issue - December 2024
This edition of Clinical Evidence reviews extended CRT-D battery performance, summarizes evidence for S-ICD, and presents initial data on the EMPOWER leadless pacemaker. An economic analysis confirms significant cost savings with extended battery longevity (2.1Ah) in CRT-D devices.
3rd Issue - September 2024
Discover the benefit of ICD implantation and the role of ATP in Primary Prevention Patients and the safety and performance data of the Modular CRM (mCRM™) System.
2nd Issue - June 2024
Explore the new data from EHRA Congress 2024, regarding the benefits of HeartLogic, SmartDelay and SMART Pass on the detection and treatment of different conditions in CRT-D patients, as well as real-world data concerning S-ICD implantation and replacement.
1st Issue – March 2024
Explore the latest real-world data on the performance of the HeartLogic™ algorithm and S-ICD, examining their potential applications in clinical practice to enhance patient outcomes.