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Advancing Care in Chronic Pancreatitis

 

Approximately 5% to 16% of patients with acute pancreatitis and 20% to 40% of patients with chronic pancreatitis develop pancreatic pseudocysts (PP).1

Symptomatic pancreatic pseudocysts may be treated surgically, percutaneously, or endoscopically. Comparative evidence consistently favours endoscopic (EUS-guided) drainage over surgical and percutaneous approaches across reinterventions, hospital stay length, and cost.2-6

 

Limitations of surgical approach

7–37%

morbidity rate with surgical management²

6%

mortality rate associated with surgery²

 

Cost of percutaneous drainage

$184,240

per patient*4

9-day

average length of hospital stay*4

*Results from a population-based pancreatic pseudocyst analysis

Beyond cost, percutaneous drainage provides limited treatment benefit as recurrence rates are high and fistulas may form,2 and the approach may create a substantially higher downstream hospital burden than EUS-guided/endoscopic drainage.3


The clinical and economic case for endoscopic drainage

4 to 2

median number of interventions with EUS-guided vs percutaneous drainage, supporting a lower repeat procedure burden for hospitals*5

~15x lower

reintervention costs associated with EUS-guided vs percutaneous drainage ($108.26 vs $1,601.54)**6

~4x lower

unplanned readmission costs with EUS-guided vs percutaneous drainage ($450.00 vs $1,717.56)**6

*In postoperative pancreatic fluid collections

**As a direct downstream-cost analogue for drainage pathway

 

Previously, endoscopic management of pancreatic pseudocysts has been difficult as available technologies were not designed for this purpose—leaving many patients without a purpose-built solution. EUS-guided drainage addresses this unmet need directly.

EUS-Guided Drainage for Chronic Pancreatitis

At Boston Scientific, we continue to advance endoscopic ultrasound (EUS) with technologies such as the Hot AXIOS™ system, enabling more efficient and effective treatment of this complex disease.

Hot Axios

Hot AXIOS™ for the Treatment of Symptomatic Pancreatic Pseudocysts

The Hot AXIOS Stent and Electrocautery-Enhanced Delivery System enables therapeutic endoscopists to safely and accurately access a pancreatic fluid collection from the gastrointestinal tract and place the Hot AXIOS Stent. Used under combined endoscopic and EUS guidance, its electrocautery-enhanced delivery system is designed to facilitate smooth, efficient access while minimising radiofrequency interference with visualisation.

Learn about the Hot AXIOS™ Stent and Electrocautery-Enhanced Delivery System


Hot AXIOS™ Learning Path

Further your professional development through our tailored Hot AXIOS™ Learning Path, combining digital and face-to-face training to equip physicians with the knowledge and skills needed to perform EUS-guided drainage procedures with confidence.

 

   

Explore our Full EUS Portfolio

Our EUS portfolio spans both diagnostic and therapeutic applications, supporting clinicians across tissue acquisition, lesion characterisation, and minimally invasive drainage procedures.

Find out more about EUS Diagnostics

Learn about the Hot AXIOS™ in the management of chronic pancreatitis

acquire-needle-clinical-settings

   

One Partner. Multiple Solutions.

At Boston Scientific, we deliver services and solutions designed to support professional education, operational efficiency and environmental sustainability.


Connect with us:

Connect with our team to access the support, resources, and information you need to stay informed and make the most of our endoscopy solutions.

*FDA Field Action review in progress for Hot AXIOS stents sizes 6mmx8mm, 8mmx8mm, and 20mmx10mm

AXIOS™ Stents Indications for Use

Electrocautery Enhanced AXIOS™ Stents (6mmx8mm*, 8mmx8mm*, 10mmx10mm, 15mmx10mm and 20mmx10mm*)

Electrocautery Enhanced AXIOSTM Stents (15mmx15mm)

Cold AXIOS™

References

1. Aghdassi et al, “Pancreatic pseudocysts – when and how to treat?” HPB 2006; 8: 432-441.

2. Shah et al, “Safety and Efficacy of Endoscopic Ultrasound-Guided Drainage of Pancreatic Fluid Collections with Lumen-Apposing Covered Self-Expanding Metal Stents.” Gastroenterol and Hepatol Oct 5, 2014; 13: 747-752.

3. Endoscopic versus percutaneous management for symptomatic pancreatic fluid collections: a systematic review and meta-analysis s-0044-102299.pdf

4. Comparison of treatment modalities in pancreatic pseudocyst : A population based study https://pmc.ncbi.nlm.nih.gov/articles/PMC6766474/

5. I mpact of endoscopic ultrasound-guided gallbladder drainage on reducing costs of reintervention and unplanned readmission: a budget impact analysis https://pmc.ncbi.nlm.nih.gov/articles/PMC9377823/

6. Endoscopic ultrasound -guided versus percutaneous drainage for the management of post-operative fluid collections after distal pancreatectomy https://link.springer.com/article/10.1007/s00464-023-10188-6

CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at www.IFU-BSCI.com. Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France.