Illustration of the ACURATE neo2™  Aortic Valve System Illustration of the ACURATE neo2 Aortic Valve System in anatomy. Supra-annular TAVI.

ACURATE neo2™ Aortic Valve System

70 k milestone

Precision today, access tomorrow

Uniquely designed with an open-frame and supra-annular leaflets, the ACURATE neo2™ Aortic Valve System delivers the performance you expect today, without restricting the access you demand tomorrow.1,2

Treat your patients today while protecting them for the future with:

Unrestricted coronary access

Very low pacemaker rates

Excellent long-term hemodynamic function

Continuing to deliver excellent patient outcomes

See the latest ACURATE neo2 Clinical Trial results 

Moderate PVL

Moderate PVL

0% Severe PVL
18.9% Mild PVL

Best in class

Permanent pacemaker rate †  

Procedural success data

success rate

Mean gradient

Mean gradient

Moderate PVL

All cause mortality

All stroke

All stroke

0% disabling stroke
at 30 days

The ACURATE neo2 PMCF study demonstrated excellent ACURATE neo2 Safety and Performance outcomes at 30 days5.

See the unique open-frame, supra-annular design in action

Proven features

ACURATE neo2™  Aortic Valve System open frame illustration

Open frame

Provides unrestricted access for future interventions

ACURATE neo2™  Aortic Valve System showing Supra-annular leafelets detail.

Supra-annular leaflets

Achieve large EOAs and single-digit gradients1

ACURATE neo2™  Aortic Valve System showing Precise positioning  mechanism

Precise positioning

Upper and lower-crown anchoring provides first-time, precise procedures 

ACURATE neo2™  Aortic Valve System showing Active PVseal™ in detail

Active PVseal™

60% larger* sealing skirt conforms to the native aortic annulus to minimize PVL

* ACURATE neo2 Valve compared to previous generation, ACURATE neo™ Valve

"PAR (Paravalvular Aortic Regurgitation) reduction demonstrated with ACURATE neo2 is very impressive and underlines the efficacy of the [valve's] active sealing skirt."

- Dr Won-Keun Kim and Prof. Helge Möllmann

JACC: Cardiovascular Interventions "Neo to Neo2 - a tiny detail with considerable impact."

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Accessories and other products

SENTINEL Cerebral Protection System

SENTINEL™ Cerebral Protection System

Protected TAVR™ with SENTINEL Cerebral Protection System (CPS) gives you the power to reduce stroke.

iSLEEVE™ Expandable Introducer Set

iSLEEVE™ Expandable Introducer Set

The low-profile iSLEEVE Introducer expands patient access into smaller and increasingly complex vasculature. 

SAFARI2™ Pre-Shaped TAVI Guidewire

SAFARI2™ Pre-Shaped TAVI Guidewire

Available in three sizes, SAFARI2 provides streamlined device delivery through optimized rail support as well as enhanced wire predictability.

*PAR (paravalvular aortic regurgitation) assessed pre-discharge in next-generation ACURATE neo2™ Valve vs. ACURATE neo™. 
**Average time to obtain commissural alignment. 
† Among pacemaker-naïve patients. Among all patients, implanted pacemaker rate= 6.1%
1. Möllmann H, Holzhey DM, Hilker M, et al. The ACURATE neo2 Valve System for transcatheter aortic valve implantation: 30-day and 1-year outcomes. Clin Res Cardiol. 2021;110:1912–1920.
2. Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS); NCT04026204. J Am. Coll. Cardiol. Intv.. 2020.
3. Buono A, et al. TAVI with self-expanding ACURATE neo2: Postprocedural hemodynamic and short-term clinical outcomes. JACC Cardiovasc Interv. 2022. doi: 10.1016/j. jcin.2022.02.027 
4. Meduri C, et al. The neo-ALIGN study. Presented at Euro PCR 2022.
5. Kim W., et al; Clinical outcomes of the ACURATE neo2 transcatheter heart valve: a prospective, multicenter, observational, post-market surveillance study, EuroIntervention 2022. DOI: 10.4244/EIJ-D-22-00914.

CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings and instructions for use can be found in the product labelling supplied with each device. Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France. Product available in the European Economic Area (EEA) only. Please check availability with your local sales representative or customer service