Early neo2 Registry core-lab results
First large, real-world clinical data on the ACURATE neo2™ Aortic Valve System*: The Early neo2 Registry
Independently studying 85% of the original study’s 554 patients, the Early neo2 Registry core-lab analysis confirmed minimized paravalvular leak rates with the ACURATE neo2 Valve and its Active PVsealTM sealing skirt.
new permanent pacemaker
moderate to severe PVL1
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First real-world analysis of patient-specific implantation techniques using different devices. The COMALIGN study demonstrated that neo-commissural alignment and optimized valve design can improve procedural success.
Best-in-class commissural alignment: ACURATE neo2 was the only self-expanding valve to 100% avoid commissural misalignment.2
0% moderate or severe commissural misalignment
ACURATE neo2 Valve
20/20 successful consecutive cases
10% moderate or severe commissural misalignment
Evolut™ R/PRO Valve
17/20 successful consecutive cases; 3 cases with non-optimal rotations
25% moderate or severe commissural misalignment
15/20 successful consecutive cases; 5 cases difficult to assess
First systematically evaluated analysis of coronary access before and after TAVI in an all-comers’ population
With 0 incidences of unsuccessful coronary cannulation, ACURATE neo demonstrated an extremely high coronary access success rate.
ACURATE neo™ Valve Platform
100% successful coronary cannulation
n = 723
82% successful coronary cannulation
n = 1233
99% successful coronary cannulation
n = 963
1. Möllmann H, Holzhey DM, Hilker M, et al. The ACURATE neo2 valve system for transcatheter aortic valve implantation: 30-day and 1-year outcomes. Clin Res Cardiol. 2021;110(12):1912–1920.
2. Bieliauskas G, Wong I, Bajoras V, et al. Patient-specific implantation technique to obtain neo-commissural alignment with self-expanding transcatheter aortic valves. J Am Coll Cardiol 2021;14(19):2097-2108.
3. Reobtain Coronary Ostia Cannulation Beyond Transcatheter Aortic Valve Stent (RE-ACCESS); NCT04026204. J Am Coll Cardiol Intv. 2020.
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