Structural Heart > LOTUS Edge™ Aortic Valve System

LOTUS Edge™ Aortic Valve System

Designed to offer complete control and predictable results, the LOTUS Edge Aortic Valve System features a proprietary frame and Adaptive Seal™ that virtually eliminate paravalvular leak (PVL), exclusive deployment technology for reduced procedural complications and 100% repositionability to optimize patient outcomes.

1. Feldman T., MD, Reardon M., MD, Rajagopal V., MD, et al. Effect of mechanically expanded vs self-expanding transcatheter aortic valve replacement on mortality and major adverse clinical events in high-risk patients with aortic stenosis - the REPRISE III randomized clinical trial. JAMA. 2018;319(1):27-37.
2. Götberg M., MD. One-year outcomes with the transcatheter LOTUS Edge Aortic Valve System; PCRLV 2018; London, United Kingdom. Includes high-surgical-risk patients with symptomatic calcific aortic stenosis from the LOTUS Edge Feasibility Study (N = 21) and the REPRISE EDGE Study (N = 15).
LOTUS Edge R&D Updates

LOTUS Edge R&D Updates

Hear about the design process for LOTUS Edge and how our commitment to continual innovation and physician collaboration helped us develop a transcatheter heart valve that offers flexibility, simplicity and placement precision.

Explore TAVI Technology

Next-Generation TAVI Technology

The LOTUS Edge Aortic Valve System is a next-generation, controlled expansion TAVI valve designed to provide unmatched freedom from paravalvular leak (PVL), precise delivery with the ability to reposition after deployment, and predictable results.

Clinical Outcomes

1-Year Primary Effectiveness Endpoint*
Superiority P <0.001

Clinical Outcomes

Proven Clinical Outcomes

In the REPRISE III TAVI clinical trial, the LOTUS Valve platform demonstrated significantly lower moderate to severe PVL, significantly lower disabling stroke rates and superior procedural outcomes versus Evolut R™/CoreValve™.

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LOTUS Edge Design

See how the LOTUS Edge Aortic Valve System was designed to offer surgical-like PVL, consistent delivery and 100% respositionability.

Indications, Safety and Warnings