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Electrophysiology / RHYTHMIA™ Cardiac Mapping System

Clinical Proof for the RHYTHMIA™ HDx Mapping System

Explore clinical articles, case studies and physician perspectives supporting the safety and efficacy of the RHYTHMIA mapping system and the INTELLAMAP ORION™ High-Resolution Mapping Catheter for both atrial and ventricular procedures.



Physician Perspectives

DIRECTSENSE Technology: the Power of Local Impedance

Learn from a board of experts how DIRECTSENSE™ Technology combines local impedance accurate measurement through the mini-electrodes embedded into IntellaNav MiFi OI ablation catheter into the RHYTHMIA HDx mapping system to reach a new dimension in ultra-high density mapping and ablation.

Dr. Noonan: Redefining Cardiac Mapping and Ablation

Dr. Daniel Noonan discusses how RHYTHMIA HDx has changed the cardiac mapping space and his practice at St. Luke's Boise Medical Center. He shares how RHYTHMIA HDx high-definition mapping system and features have improved his workflow, his approach to complex cases and his patients.

Dr. Yang: Unparalleled Clarity in Cardiac Mapping Video

Listen to Dr. Felix Yang from Maimonides Medical Center in New York City talk about how RHYTHMIA HDx has surpassed the clarity of other cardiac mapping and navigation systems. “Whereas frequently we only have a rough idea of how an arrhythmia would propagate and we may deliver empiric ablation lines to treat them, the high-definition maps acquired by the system allow us to actually see what are the critical components of an arrhythmia circuit.”


Clinical Data

Angel Ferrero et al. (2018)

Usefulness of mini-electrode catheter in gap identification in Redo AF procedures

Antonio Berruezo et al. (2017)

Mini-Electrodes Help Identify Hidden Slow Conduction during Ventricular Tachycardia Substrate Ablation

Caputo et al.  (2018)

Cavo-tricuspid isthmus ablation using a novel mapping catheter with mini electrodes to enhance signals quality

Franco et al.  (2017)

Usefulness of High Resolution Mapping with Mini-Electrodes to Select Ablation Site in Complex Arrhythmias 

Anter, E., et al. | Circulation | 2016

High-Resolution Mapping of Post-Infarction Reentrant Ventricular Tachycardia: Electrophysiological Characterization of the Circuit

Anter, E., et al. | Heart Rhythm | 2015

Pulmonary Vein Isolation Using the Rhythmia Mapping System: Verification of Intracardiac Signals Using the Orion Mini-Basket Catheter

Anter, E., et al. | Heart Rhythm | 2016

Evaluation of a Novel High-Resolution Mapping Technology for Ablation of Recurrent Scar-Related Atrial Tachycardias

Bollmann, A., et al. | J Cardiovasc Electrophysiol | 2016

Initial Experience with Ultra High-Density Mapping of Human Right Atria

Bollmann, A., et al. | Int J Clin Exp Med | 2015

Percutaneous Transapical Access for Pulmonary Vein Mapping and Ablation in a Porcine Model with a New High-Density Electroanatomical Mapping System

Bun, S.S., et al. | Circ J | 2016

Ultra-High-Definition Mapping of Atrial Arrhythmias

Daccarett, M., et al. | Heart Rhythm | 2017

High Density Activation Map Guided Ablation Results in Improved Pulmonary Vein Entrance Block Heart Rhythm. Page 18.

EP Europace Supplements | Advanced Mapping Capabilities | January 2019

Laţcu, D.G., et al. | Circulation: Arrhythmia and Electrophysiology | 2017

Selection of Critical Isthmus in Scar-Related Atrial Tachycardia Using a New Automated Ultrahigh Resolution Mapping System

Mantziari, L., et al. | JACC: Clinical Electrophysiology | 2015

Utility of a Novel Rapid High-Resolution Mapping System in the Catheter Ablation of Arrhythmias: An Initial Human Experience of Mapping the Atria and the Left Ventricle

Nakagawa, H., et al. | Circ Arrhythm Electrophysiol | 2012

Rapid High Resolution Electroanatomical Mapping: Evaluation of a New System in a Canine Atrial Linear Lesion Model

Pathik, B. and J.M. Kalman | Circulation: Arrhythmia and Electrophysiology | 2017

Perceiving the Imperceptible in Atrial Macro-Reentry: Ultrahigh Resolution Mapping to Characterize the Critical Isthmus

Ptaszek, L.M., et al. | J Interv Card Electrophysiol | 2013

Rapid Acquisition of High-Resolution Electroanatomical Maps Using a Novel Multielectrode Mapping System

Rottner, L., et al. | J Cardiovasc Electrophysiol | 2017

Direct Comparison of Point-by-Point and Rapid Ultra High-Resolution Electroanatomical Mapping in Patients Scheduled for Ablation of Atrial Fibrillation

Santoro, F., et al. | Clin Res Cardiol | 2017

Endocardial Voltage Mapping of Pulmonary Veins with an Ultra-High Resolution System to Evaluate Atrial Myocardial Extensions

Schaeffer, B., et al. | J Cardiovasc Electrophysiol | 2016

Characterization, Mapping, and Ablation of Complex Atrial Tachycardia: Initial Experience with a Novel Method of Ultra High-Density 3D Mapping

Sohns, C., et al. | Clin Res Cardiol | 2016

First Clinical Experience Using a Novel High-Resolution Electroanatomical Mapping System for Left Atrial Ablation Procedures

Tanaka, Y., et al. | Heart Rhythm | 2015

Utility of High-Resolution Electroanatomic Mapping of the Left Ventricle Using a Multispline Basket Catheter in a Swine Model of Chronic Myocardial Infarction

Thajudeen, A., et al. | Pacing and Clin Electrophysiol | 2015

Correlation of Scar in Cardiac MRI and High-Resolution Contact Mapping of Left Ventricle in a Chronic Infarct Model

Viswanathan, K., et al. | Heart Rhythm | 2017

Evaluation of a Novel High-Resolution Mapping System for Catheter Ablation of Ventricular Arrhythmias


Case Studies

Dr. Cireddu et al.: Complex electrograms annotation in activation maps: LUMIPOINT software tool in a hybrid AF redo case

Dr. Bianchi et al.: A Minimal Fluoroscopic Approach TOAVNRT Ablation with Rhythmia HDx

Prof. Ignacio García Bolao Live Case Study: Paroxysmal Atrial Fibrillation Ablation procedure with DirectSense™ Technology

Prof. Ignacio García Bolao (Chief of Electrophysiology Department at Clínica Universidad de Navarra, Spain) presents his latest experience with Rhythmia HDx™  Mapping System together with DirectSense™, technology, which provides the user with real local impedance information.


Learn from Professor of Medicine and Cardiac Electrophysiology Reza Wakili from University of Duisburg-Essen, Germany the benefits of the local impedance included in the new DirectSense Technology and how electrical contact meets ultra high-density and ultra high-resolution 3D electroanatomical maps to drive to a successful Pulmonary Vein Isolation Ablation on a Paroxysmal Atrial Fibrillation patient.

Dr. Derval – RHYTHMIA HDx is a game changer

Dr. Nicolas Derval shares findings from his study using the RHYTHMIA HDx™ Mapping System and discusses why he believes the RHYTHMIA HDx system is a game changer in the mapping and navigation space.

Dr. Maury – RHYTHMIA HDx has a unique ability to collect a large amount of points

Dr. Philipe Maury describes case types to demonstrate the RHYTHMIA HDx™ Mapping System’s ability to collect a large amount of points and to show how its unique annotation algorithm leads to reliable maps.

Dr. Santangeli – RHYTHMIA HDx designed with the intent of high-density and reliable cardiac mapping

“The RHYTHMIA™ HDx Mapping System is a really innovative system of mapping complex arrhythmias, and has been designed to think with the intent of providing high-density, reliable, and quick high-resolution mapping to diagnose the mechanism underlying complex arrhythmias, and to find the substrate underlying those arrhythmias as well.”

Dr. Gallagher’s Live Case Study: Treatment of Complex Scar-Related Atrial Arrhythmias

This case highlights how the density, resolution and automation of the RHYTHMIA HDx Mapping System helped facilitate Dr. Peter Gallagher’s assessment and treatment strategy for his patient’s set of complex scar-related arrhythmias.

Dr. Wong: Ablation of Atrial and Dual-loop Ventricular Tachycardia (PDF)

Download a PDF of Dr. Tom Wong’s case study of a 54-year-old patient who had previously gone through a Ross Procedure but, years later, was admitted to the hospital with two different types of tachycardias.

Close-up of a RHYTHMIA HDx high-definition cardiac map.

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Physician using a Boston Scientific electrophysiology product.

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