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PROACTIF: The largest, prospective, real-world Y-90 study with TheraSphereTM for the treatment of liver malignancies
First multicentre, 1259 patient study that builds on previously published TheraSphere landmark trials which span the Barcelona Clinic Liver Cancer (BCLC) guidelines
Data from 34 sites using contemporary techniques and dosing
Evaluate effectiveness, safety and patient quality of life (QoL) with TheraSphere treatment in real-world clinical practice, and to identify clinical and dosimetric factors associated with survival
Overall survival (OS) and quality-of-life (QoL)
Safety, conversion to surgery and factors associated with OS
Guiu et al. Effectiveness and Safety of Selective Internal Radiation Therapy using Yttrium-90 Glass Microspheres for Hepatocellular Carcinoma: Real-world Results from the Multi-center Prospective PROACTIF Cohort of 989 Patients. eClinicalMedicine. Published Online https://doi.org/10.1016/j.eclinm.2026.103884
HCC = hepatocellular carcinoma
*ICCA = intrahepatic cholangiocarcinoma
Caution:
The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at www.IFU-BSCI.com. Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France.
TheraSphere is a registered trademark of Theragenics Corporation, used under license by Boston Scientific Medical Device Limited, a wholly owned indirect subsidiary of Boston Scientific Corporation.
