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Pancreatic Cancer

Clinical Challenge

  • Mean survival is 6-121,2 months for the 80% of pts who are non-surgical candidates.
  • Mean stent patency (metal): 72d3.
  • Therefore, more than half of the patients may outlive the patency of their stents.
  • Malignant biliary obstruction and cholangitis are the most commonly seen complication in patients suffering from pancreas tumors3.

Clinical Goal

Provide and maintain biliary decompression and drainage

Literature Highlights

Data is for Ablation + stenting vs stenting alone is mixed, depending upon the study.

  • Mean SEMS Patency Improvement: 97.7%, 143+109 vs 72.3+37, p=0.013
  • Mean SEMS Patency 472d vs 374, p=0.6694 (statistically equivalent)
  1. Sharaiha, R et al, Comparison of Metal Stenting with Radiofrequency Ablation Versus Stenting Alone for Treating Malignant Biliary Strictures: Is There an Added Benefit?, Dig Dis Sci, June 2014
  2. Pancreatica.org
  3. Kadayifci, Radiofrequency ablation for the management of occluded biliary metal stents, Endoscopy, 2016
  4. Kallis et al., Analysis of Endoscopic RFA of Biliary Malignant Stricture in Pancreatic Cancer Suggest Potential Survival Benefit, Digestive Diseases, 2015
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