What is Pulsed Field Ablation? - Boston Scientific

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How PFA Works

CARDIAC MAPPING AND ABLATION THERAPIES

Overview

What is PFA?

Clinical Evidence

Educational Resources

Electrophysiology / Cardiac Mapping and Ablation Therapies / Farapulse™ Pulse Field Ablation System / What is PFA?

The FARAPULSE™ PFA System works differently.

Panoramic procedure view of ablation using FARAPULSE PFA System (video thumbnail)

The Shape of the Future.

The FARAPULSE Pulsed Field Ablation System produces durable, effective lesions and minimises collateral damage risks associated with thermal energy sources.¹ Validated more than any other pulsed field ablation (PFA) system, FARAPULSE PFA is pioneering possibilities for the future of tissue-selective ablation.

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Collateral-tissue safety with proven PVI durability.

Tissue-selective ablation.

Unlike thermal energy applications, the FARAPULSE Pulsed Field Ablation System uses a proprietary waveform to ablate cardiomyocytes which have lower electric field damage thresholds while preserving surrounding tissue — despite exposure to the field.²

Associate Prof. Kars Neven on FARAPULSE PFA Lesion Science

Discover more about FARAPULSE PFA lesion science by listening to Associate Prof. Kars Neven impart his knowledge.

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Irreversible electroporation.³

Proven procedural prescription for successful PVI.

Pulsed field ablation is highly parameter-dependent, and slight variations in polarity, waveform, catheter electrodes, pulse characteristics, or applications can be the difference between acute or chronic success.⁴The FARAPULSE Pulsed Field Ablation System was optimised through years of iterations to define and validate the dose with catheter, waveform, and application sequence.

Pulmonary Vein Durability on Remapping¹

Prospective Remaps at 93 ± 30 days

All three cohorts showed 100% acute PVs isolated, though lesion durability varied significantly at remap (~3 months). Acute isolation alone is not enough to assure durable lesions — remapping data validates the FARAPULSE Pulsed Field Ablation System’s optimal dosing and applications for long-term success.¹

Pulsed field ablation offers [an] effective method for atrial fibrillation ablation, with a reduced risk of collateral damage...
I would strongly recommend having PFA in the EP toolbox.

Prof. Gábor Széplaki
Mater Private Hospital, Dublin

Interested in hearing an expert’s thoughts on lesion creation with FARAPULSE PFA? Listen to what Prof. Tobias Reichlin has to say.

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Learn PFA from the experts.

Can Pulsed Field Ablation Meet All Your Needs?

Prof. KR Julian Chun presents the updated experience from the CCB group with the FARAPULSE PFA System.

Fundamental Science on Pulsed Field Ablation - Dr Kars Neven

Fundamental Science of Pulsed Field Ablation

Prof. Kars Neven presents an overview of PFA, its history, pre-clinical data, system design, and more.

On-demand online training.

Put your understanding of pulsed field ablation to the test with a guided overview course on the EDUCARE platform — accessible 24/7 from your desktop, laptop, or mobile device.

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