TORe: A tailored procedure for post-bariatric patients

A clinically proven, minimally invasive option for weight regain after gastric bypass.

Introducing Transoral Outlet Reduction (TORe)

transoral-outlet-reduction-tore

An estimated 15,000 endoscopic revisions of bariatric procedures performed worldwide.1

More than 150 clinical papers and abstracts have been published on TORe.2

Transoral Outlet Reduction (TORe) is a minimally invasive procedure designed for patients who have regained weight after gastric bypass. By tightening the connection between the stomach and small intestine, TORe helps restore portion control and supports long-term weight loss.

No incisions or scars

Most patients typically go home the same day

Low adverse event rate3

   

How the TORe procedure is performed

TORe is performed under general anesthesia by a trained gastroenterologist or surgeon, using the OverStitch™ System. The procedure involves a flexible scope inserted through the mouth, avoiding incisions and minimizing downtime. It safely restores the stomach’s restrictive function to help patients lose weight again, with most patients typically discharged the same day.

Curious to learn more about TORe? Here’s how it works:

                 

Clinical evidence

6%

Proven Weight Loss Results

In a large meta-analysis, patients who underwent TORe saw an average of 6% total body weight loss at 12 months.⁴

9-12%

Latest Technique

Latest studies using the purse-string approach report 9-12% TBWL at 12 months.5,6

5&7 y.

Support Long-Term Outcomes

Long-term studies support durable weight loss at 5 and 7 years.5,7

A comparative study demonstrated a lower rate of adverse events with TORe compared to surgical revisions, whilst achieving similar outcomes in long-term efficacy.3
 

  TORe n=31LAP n=31p-value
Effectiveness at 5 years11.5% TBWL13.1% TBWL0.67
Adverse events6.5%29.0%0.04
Safety profile0% SAE* rate19.4% SAE rate0.024

Dolan, et al; Gastrointestinal Endoscopy. 2021

  • Matched cohort population
  • Multicentric
  • Long follow-up studies: 5yrs
*Values are n (%). Adverse event rate comparison between endoscopic and surgical gastrojejunal anastomosis revision. Serious adverse events were determined in reference to the American Society for Gastrointestinal Endoscopy lexicon for reporting endoscopic adverse events and the National Surgical Quality Improvement Program. Early events defined as those occurring within 30 days of revision.

Key Resources

TORe Physician Brochure

Filename
TORe-Physician-Brochure.pdf
Size
1 MB
Format
application/pdf
Download

Clinical Evidence in Revisional Procedures

Filename
leaflet-clinical-evidence.pdf
Size
919 KB
Format
application/pdf
Download

Resources for Patients

Discover comprehensive resources tailored for TORe patients across the UK, Spain, Italy, Germany, and France.

Patient Perspective: Alessia‘s TORe Journey

Listen to Alessia’s story as she shares her TORe journey.

Transoral Outlet Reduction (TORe) for patients in the UK

Riduzione dell'anastomosi per via transorale per i pazienti in Italia

Transorale Outlet-Reduktion für Patienten in Deutschland

Reducción endoscópica transoral para pacientes en España

Réduction de l'anastomose gastro-jéjunale pour le patients en France

    

References

  1. Estimates based on Apollo Endosurgery internal sales data, 2019
  2. Data on file.
  3. Dolan, et al; Endoscopic versus surgical gastrojejunal revision for weight gain in Roux-en-Y gastric bypass patients: 5-year safety and efficacy comparison. Gastrointestinal Endoscopy. 2021.
  4. Jaruvongvanich V, et al. Endoscopic full-thickness suturing plus argon plasma mucosal coagulation versus argon plasma mucosal coagulation alone for weight regain after gastric bypass: a systematic review and meta-analysis. Gastrointestinal Endoscopy. 2020.
  5. Jirapinyo P, et al. Five-year outcomes of Transoral Outlet Reduction for the treatment of weight regain after Roux-en-Y gastric bypass. Gastrointestinal Endoscopy. 2020.
  6. Meyers, et al. Factors associated with weight loss after endoscopic Transoral Outlet Reduction (TORe). Gastrointestinal Endoscopy. Volume 95, No. 6S. 2022.
  7. Jirapinyo, et al. Seven-year Outcomes of Transoral Outlet Reduction for the Treatment of Weight Regain After Roux-en-Y Gastric Bypass. Gastrointestinal Endoscopy. 2020. Subset of patients included in study are also represented in 5-year data
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