The IFSO Bariatric Endoscopy Committee endorses Endoscopic Sleeve Gastroplasty (ESG) as an effective and valuable treatment for obesity.1
ESG is a minimally invasive weight loss procedure that offers a safe and clinically effective alternative to surgery.
ESG is particularly beneficial for patients with class I and II obesity, as well as for those with class III obesity who are not suitable candidates for metabolic bariatric surgery.1
How the ESG procedure is performed
A trained gastroenterologist or surgeon who performs bariatric procedures uses the OverStitch™ system to create a series of plications in the stomach, forming a sleeve endoscopically. Over time, scarring and bridging tissue help to maintain the newly formed gastric shape. In addition to reducing volume, studies have shown that the ESG procedure delays gastric emptying, resulting in prolonged satiety.2, 3
Meaningful results
Clinical evidence
Download our leaflet for a concise, evidence-based overview of ESG, showcasing the latest clinical data and insights that support its safety and efficacy.
The MERIT Study
The Multicenter Endoscopic Sleeve Gastroplasty Randomized Interventional Trial (MERIT)2 was conducted to evaluate the safety and efficacy of ESG compared to a medically monitored programme of diet and lifestyle modification.
Over a 2-year period, 209 patients between the ages of 21-65, with class 1 or 2 obesity were included in the study. All of whom agreed to comply with the necessary dietary restrictions.
49%
Excess body weight loss 12 months after the procedure.2
2%
In the MERIT Study, ESG had a 2% rate of serious adverse events (Clavien-Dindo grade III or higher).2
Resources for Patients
Discover comprehensive resources tailored for ESG patients across the UK, Italy, Germany, and Spain.
Patient Perspective: Joanna’s ESG Journey
Listen to Joanna’s story as she shares her transformative weight loss journey with ESG.
Key Resources
Adopting ESG – Interview with Dr. Lubbe
Dr. Lubbe shares what led her to adopt the endoscopic approach in her bariatric department, with a focus on the role of ESG.
Alternative bariatric procedures
- Laparoscopic sleeve gastrectomy (LSG), also referred to as vertical sleeve gastrectomy, is a restrictive bariatric procedure predominantly performed via laparoscopy. During LSG, approximately 75-85% of the stomach is resected along the greater curvature. This procedure induces significant neurohormonal and bile signaling modifications, contributing to its metabolic efficacy.4
- Roux-en-Y gastric bypass (RYGB) involves the exclusion of a portion of the stomach and proximal intestine, with the distal intestine reconfigured into a Y-configuration. This allows for the passage of ingested food from the upper gastric pouch through the Roux limb, facilitating both weight loss and metabolic benefits, independent of weight reduction.4
