InhibiZone™

Antibiotic Surface Treatment

Infection remains one of the most serious complications associated with inflatable penile prosthesis surgery. Preventing bacterial colonisation during the early post-operative period is essential to help reduce the risk of infection and revision surgery.

The AMS 700™ Inflatable Penile Prosthesis is the only antibiotic-impregnated IPP featuring InhibiZone Antibiotic Surface Treatment. Integrated into the silicone layers of the implant, InhibiZone is clinically proven to help reduce infection-related revisions, including in challenging patient populations.1-3

Why trust InhibiZone?

Built into the implant

The only antibiotic-impregnated IPP.

Backed by clinical evidence

18 years of data.

Fixate efficiently with Boston Scientific's CSP portfolio.

Designed for better procedures

No dipping. No mixing. No unnecessary steps.

How it works?

InhibiZone is a proprietary combination of rifampin and minocycline that is impregnated into the silicone layers of the AMS 700 Inflatable Penile Prosthesis. Unlike surface-applied antibiotic solutions, the antibiotics are gradually released during the critical post-operative period to help prevent microbial colonisation of the device surface.

Bacterial colonisation of an implant surface can occur within the first few days after implantation. InhibiZone is designed to provide gradual antibiotic release over approximately 14 days, covering this critical agreed period.

Clinical evidence

Backed by more than 18 years of published clinical evidence, InhibiZone has demonstrated reduced infection-related revisions across original implants, revision procedures and high-risk patient populations.

56%

Reduction (from 2.5% to 1.1%) in revisions due to infection in first-time implant patients1

32%

Reduction (from 3.7% to 2.5%) in secondary revision procedures due to infection2

65%

Reduction (from 4.17% to 1.47%) in initial revisions due to infection in high-risk patients with diabetes3

Discover the clinical data

Not all antibiotic delivery mechanisms are the same.

InhibiZone™

  • Antibiotics impregnated into the silicone
  • Gradual release
  • No dipping
  • Ready to use

Surface-applied antibiotic coatings

  • Antibiotics applied before implantation
  • Rapid release
  • Additional preparation required

Protection you can trust.

Discover how InhibiZone is integrated into the AMS 700 Inflatable Penile Prosthesis.

Learn more about AMS 700

AMS 700 Inflatable Penile Prosthesis Indications, Safety, and Warning

References:

1. Carson CC III, Mulcahy JJ, Harsh MR. Long-term infection outcomes after original antibiotic-impregnated inflatable penile prosthesis implants: up to 7.7 years of follow-up. J Urol. 2011;185:614–618.
2. Nehra A, Carson CC III, Chapin AK, et al. Long-term infection outcomes of a 3-piece antibiotic-impregnated penile prosthesis used in replacement implant surgery. J Urol. 2012;188:899–903.
3.Mulcahy JJ, Carson CC III. Long-term infection rates in diabetic patients implanted with antibiotic-impregnated versus nonimpregnated inflatable penile prostheses: 7-year outcomes. Eur Urol. 2011;60:167–172.

CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at www.IFU-BSCI.com. Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France. Bench Test results may not necessarily be indicative of clinical performance. Images provided courtesy of Boston Scientific. All trademarks are the property of their respective owners.

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