Healthcare professionals / Gastroenterology / HabibTM EndoHPB Bipolar Radiofrequency Catheter / Cholangiocarcinoma Stricture Management

Cholangiocarcinoma (Cca) Stricture Management

Clinical Challenge
  • Mean survivalis 6-121 months for the 60% of pts who arenon-surgical candidates
  • Mean stentpatency(plastic/metal): 3.4 / 8.4mo.2,3
  • Therefore, more than half of the patients may outlive thepatency of their stents
  • Patients typically experience biliary obstruction, which leads tocholangitis and liver failure, with is also a cause of death3.

Clinical Goal for RFA

Proactively manage patients with RFA to prolong patency

Literature Highlights

Data is for Ablation + stenting vs stenting alone

  • Average Patency Improvement:
    • Plastic 3.4 vs. 6.8 mo(p=0.02) 2
    • Metal 8.4 vs. 9.5mo (p=0.024) 3
  • Complication rates show no significant difference 6.36% vs. 9.1% p=0.672
Disclaimer: Results from different clinical investigations are not directly comparable. Information provided for educational purposes only.
  1. Sharaiha, R et al, Comparison of Metal Stenting with Radiofrequency Ablation Versus Stenting Alone for Treating Malignant Biliary Strictures: Is There an Added Benefit?, Dig Dis Sci, June 2014
  2. Yang, Efficacy and safety of endoscopic radiofrequency ablation for unresectable extrahepatic cholangiocarcinoma: a randomized trial,  Endoscopy 2018
  3. Liang et al., metal Stenting with or w/o Endobiliary RFA for Unresectable Extrahepatic Cholangiocarcinoma, Journal of Cancer Therapy, 2015, 6, 981-982


All trademarks are the property of their respective owners.
CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings and instructions for use can be found in the product labelling supplied with each device.
Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries. This material not intended for use in France.
Product available in the European Economic Area (EEA) only. Please check availability with your local sales representative or customer service.
Top