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Healing Viewed Through Angioscopy
Synchrony™ Bioabsorbable Polymer Coating is applied only to the abluminal side of the stent to stimulate healthy endothelialization.
Discover why Dr. Antonio Colombo from San Rafaelle in Milan, Italy uses SYNERGY in his daily practice.
SYNERGY Stent engineers explain the science behind the design goal to provide optimal healing and to improve patient outcomes, among all types of complexities.
This OCT study of LAD stents 2-months post-implant show consistent, full strut coverage of the SYNERGY Stent compared to a bioabsorbable vascular scaffold (BVS).*
Drug-eluting stent technology has shown encouraging efficacy compared to bare metal stents, significantly reducing restenosis and revascularization procedures. Still, there remains a concern for being able to treat ever-increasing complex lesions, ensuring proper healing, and managing dual antiplatelet therapy (DAPT).
What if there was a technology that offered the benefits of being able to improve the ability to acutely treat complex lesions, improve the healing properties, and potentially free selected patients from long-term DAPT?**
Designed to help patients, including those with complex cases, heal from day one and beyond.
Abluminally-coated stent technology synchronizes the release of drug elution and polymer absorption for optimal healing within the vessel.1
The SYNERGY Stent’s ultra-thin struts show more rapid healing compared to thicker stent strut designs in clinical cases and in preclinical research.2,3
Polymer is gone when it’s no longer needed—shortly after the drug is completely eluted at three months, which minimizes polymer exposure in the vessel.4
| STENT LENGTH | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ø (mm) |
8 | 12 | 16 | 20 | 24 | 28 | 32 | 38 | 48 | Over Expansion Capability |
| 2.25 | H7493926208220 | H7493926212220 | H7493926216220 | H7493926220220 | H7493926224220 | H7493926228220 | H7493926232220 | H7493926238220 | 3.50 | |
| 2.50 | H7493926208250 | H7493926212250 | H7493926216250 | H7493926220250 | H7493926224250 | H7493926228250 | H7493926232250 | H7493926238250 | H7493926248250 | 3.50 |
| 2.75 | H7493926208270 | H7493926212270 | H7493926216270 | H7493926220270 | H7493926224270 | H7493926228270 | H7493926232270 | H7493926238270 | H7493926248270 | 3.50 |
| 3.00 | H7493926208300 | H7493926212300 | H7493926216300 | H7493926220300 | H7493926224300 | H7493926228300 | H7493926232300 | H7493926238300 | H7493926248300 | 4.25 |
| 3.50 | H7493926208350 | H7493926212350 | H7493926216350 | H7493926220350 | H7493926224350 | H7493926228350 | H7493926232350 | H7493926238350 | H7493926248350 | 4.25 |
| 4.00 | H7493926208400 | H7493926212400 | H7493926216400 | H7493926220400 | H7493926224400 | H7493926228400 | H7493926232400 | H7493926238400 | H7493926248400 | 5.75 |
The SYNERGY Stent design goals are to address needs surrounding complex PCI. As a result, Boston Scientific established a robust clinical trial program and is supporting investigator-sponsored research5 (ISR) that will study the SYNERGY Stent in many different patient populations that interventional cardiologists see in their everyday practice.
The SYNERGY Everolimus Eluting Coronary Stent System is indicated for improving coronary luminal diameter in patients with symptomatic ischemic heart disease, including patients with acute myocardial infarction and patients with concomitant diabetes mellitus due to discrete de novo native coronary artery lesions. The SYNERGY Stent System is also indicated for treatment of patients presenting with:
Added recommendations include: For treatment of occluded vessels, contrast visualization of the distal vessel to confirm position of guidewire within the lumen is recommended. For in stent restenosis, where details of the original stent are known, the expanded inner diameter of the new stent should not exceed the dilation limits of the original stent. Where details of the original stent are not known, the expanded inner diameter of the new stent should not exceed the reference vessel diameter. When treating Bifurcations, care must be exercised to access the secondary vessel via the repeating geometry in the body of the stent within the primary vessel.
Long Lesions represent a complex lesion subset that is associated with increased safety related events, reduced efficacy and increased procedure time.*** SYNERGY™ BP Stent was designed for quality healing and safety over time. With the addition of a 48mm length SYNERGY has a complete size matrix to address these complex lesions.The SYNERGY™ BP Stent, with its abluminal, bioabsorbable polymer, shows more complete stent coverage compared to permanent polymer stents.
and stay up to date with the latest advances for optimizing revascularization
^ The updated Directions for Use will also include an update on the current “Pre-and Post-Procedure Antiplatelet Regimen”:
In selected higher risk patients where the physician determines that the risks outweigh the benefits of continued DAPT, it may be reasonable to interrupt or discontinue therapy after 1 month based on low stent thrombosis rates and no observed increased risk for stent thrombosis as shown in the current literature. Patients who require premature discontinuation of antiplatelet therapy should be monitored closely and have their antiplatelet therapy restarted as soon as possible per the discretion of their treating physicians.
