About MultiSENSE
Overview
MultiSENSE was an international, multicenter, non-randomized feasibility study designed to determine how ambulatory sensor measurements change with worsening heart failure (HF).
Goals
Develop and validate a multi-sensor algorithm for the early detection of worsening heart failure.
Conclusions
HeartLogic multi-sensor index and alert algorithm provide a sensitive and timely predictor of impending heart failure decompensation.1
The Journey
![Icon of a piece of paper with a heartbeat going across.](https://www.bostonscientific.com/en-US/medical-specialties/electrophysiology/heartlogic-heart-failure-diagnostic/clinical-data/multisense/_jcr_content/fullBleedTileContent-par/fullbleedtile_553786/maincontentFullBleed-par/image_copy_copy_copy_654435301.img.research-icon.jpg)
Research
- 10+ years research
- Data analysis from 12 clinical trials
- Extensive HF clinic customer visits
![Chart showing the HeartLogic sensitivity and unexplained alert rates per patient-year.](https://www.bostonscientific.com/en-US/medical-specialties/electrophysiology/heartlogic-heart-failure-diagnostic/clinical-data/multisense/_jcr_content/fullBleedTileContent-par/fullbleedtile_553786/maincontentFullBleed-par/image_copy_copy_copy_710192350.img.study-graph.jpg)
![doctor doctor](/content/dam/bostonscientific/ep/portfolio-group/heartlogic-heartfailure-diagnostic-ep/ep_heart_logic_ep_clinical_data_physician_video-desktop.png)
“From the time an alert occurs until the heart failure event—the median time is 34 days. That gives us a great opportunity to change the course of the future.”
John P. Boehmer, MD
Identifying High-Risk Patients
The MultiSENSE study demonstrated HeartLogic Heart Failure Diagnostic’s ability to identify high-risk patients, which may allow clinicians to focus on patients at highest risk while maintaining surveillance of low-risk patients.
![Read the Article Read the Article](/content/dam/bostonscientific/ep/portfolio-group/heartlogic-heartfailure-diagnostic-ep/multisense/read-article-BG-d.jpg)
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References
1. Boehmer JP, Hariharan R, Devecchi FG, et al. A multisensor algorithm predicts heart failure events in patients with implanted devices: results from the MultiSENSE study. JACC Heart Fail. 2017 Mar;5(3):216-225. doi: 10.1016/j.jchf.2016.12.011
2. Gardner R, Singh J, Stancak B, et al. HeartLogic multisensor algorithm identifies patients during periods of significantly increased risk of heart failure events: results from the MultiSENSE study. Circ Heart Fail. 2018;11(7):e004669. doi: 10.1161/circheartfailure.117.004669