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Close-up of EKOS Endovascular System catheter, with ultrasonic pulses emanating from it
EKOS™ Endovascular System

Proven History and Technology

The First Choice in the Interventional Treatment of PE

Vascular Surgery / EKOS Endovascular System / Proven History and Technology


The New Standard of Care for Pulmonary Embolism Treatment

EKOS was the first interventional device for treating PE. Today, it’s trusted by more clinicians than any other PE device.

Untitled Document
  • 2005 First Patient Case
  • 2008 EKOS Receives Peripheral Vascular Indication
  • 2008 First DVT Data Published
  • 2014 EKOS Receives PE Indication
  • 2014 ULTIMA – Level 1 PE Data Published
  • 2015 SEATTLE II - Pivotal PE Trial Published
  • 2018 OPTALYSE PE – Optimized PE Protocol; Long-Term Patient Outcomes
  • 2018 ACCESS PTS – First Chronic DVT Data Published
EKOS catheter
Visualization of acoustic waves in blue

One 15-minute Procedure Can Deliver Dramatic Results

Proven to yield safe and effective results, EKOS is low risk and reliable. Because of EKOS’ small size, it allows further reach into smaller distal pulmonary vessels.

How EKOS Works

EKOS ultrasound technology unwinds and thins fibrin strands to expose more drug receptor sites; acoustic streaming drives the drug deeper into the clot.

Before EKOS Ultrasound
Thick, dense fibrin strands
After EKOS Ultrasound
Thinner, less dense fibrin strands
Background image of vascular system and lungs with icons

Clinically Proven to be Safe and Reliable with Long-Term Outcomes


  • Minimally invasive, 15-minute procedure that is easy to perform
  • Requires less lytic agent: as low as 8 mg tPA used1
  • Prescribed protocol that allows for predictable procedural workflow and proven patient outcomes
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Indications, Safety and Warnings

1. Tapson V et al. A randomized trial of the optimum duration of acoustic pulse thrombolysis procedure in acute intermediate-risk pulmonary embolism.  JACC: Cardiovascular Interventions 2018; 11(14):1401-1410.