POLARIS

Multi-Modality Guidance System

Pd/Pa = iFR, like °C = °F

“Pd/Pa seems to offer a universal resting physiological metric with equivalent agreement to iFR. Although not numerically identical, 1 index can be linearly transformed into the other, much like the conversion of units of temperature. Using the binary cutoff of iFR ≤0.89 as a reference standard, Pd/Pa showed excellent agreement according to ROC curve analysis and the best cutoff value of Pd/Pa was ≤0.91.”

-Kobayashi Y, et al. JACC Oct 2017.

 

Key Resources

COMET Pressure Guidewire OPTICROSS HD Imaging Catheters
 

Pd/Pa

iFR

Single Cutoff1

≤0.91

≤0.89

Hybrid Algorithm2,3

0.88-0.97

0.86-0.93

FDA-Cleared4

✔

✔

Inclusion in Appropriate Use Criteria5,6

✔

✔

SCAI/ACC Reimbursement Recommendation7

✔

✔

Equivalent Correlation to FFR8,9,10,11

✔

✔

Equivalent Correlation to CFR12

✔

✔

Results Integrate into All Major Hemodynamic Systems

✔

X

ECG-free Algorithm Widely Available13

✔

X

Workhorse Pressure Guidewire Available

✔

X

Pd/Pa and iFR contain 95% of the same information11

 

Pd/Pa and iFR Compared to Other Physiologic Indices

Resting Measurements vs. FFR
Resting Measurements vs. CFR<sup>12</sup>
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