Nykamp & Laurich Study
EKOS Endovascular System PE Clinical Studies

Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Lytic Therapy in Acute Pulmonary Embolism With and Without Haemodynamic Instability
Nykamp M et al. J Vasc Surg: Venous and Lymphatic Disorders 2015: 3(5) 251-7

Key Results

Acute PE patients treated with EKOS therapy showed:

• Complete resolution of cardiac dysfunction in 64% of patients immediately post procedure.
• Direct pulmonary artery pressure showed an average reduction of 40.2%.
• No deaths through 90 days of follow-up and no major periprocedural bleeding events.
• Fewer adverse events at 2-year follow-up compared to patients treated with anticoagulation only.
• Shorter average length of stay: EKOS treated = 3.2 days vs. AC = 6.7 days.
  

Conclusions

EKOS therapy is an effective PE treatment for reducing pulmonary artery pressures and resolving haemodynamic abnormalities, with excellent mortality and complication rates.