Nykamp & Laurich Study
EKOS Endovascular System PE Clinical Studies
Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Lytic Therapy in Acute Pulmonary Embolism With and Without Haemodynamic Instability
Nykamp M et al. J Vasc Surg: Venous and Lymphatic Disorders 2015: 3(5) 251-7
Acute PE patients treated with EKOS therapy showed:
- Complete resolution of cardiac dysfunction in 64% of patients immediately post procedure.
- Direct pulmonary artery pressure showed an average reduction of 40.2%.
- No deaths through 90 days of follow-up and no major periprocedural bleeding events.
- Fewer adverse events at 2-year follow-up compared to patients treated with anticoagulation only.
- Shorter average length of stay: EKOS treated = 3.2 days vs. AC = 6.7 days.
EKOS therapy is an effective PE treatment for reducing pulmonary artery pressures and resolving haemodynamic abnormalities, with excellent mortality and complication rates.