Use FFR to Determine the Culprit Lesion
A strong body of clinical evidence supports FFR usage to identify ischemia producing lesions. Partner with Boston Scientific to access a complete set of PCI Guidance tools that will help you master the complex.
...the maximum flow down a vessel in the presence of stenosis compared to maximum flow in the hypothetical absence of the stenosis.
FFR <0.80 is the Cutoff Used in Most Clinical Studies (FAME)*
- FFR < 0.75 was validated against the 3 gold standard tests to correlate with ischemia with 100% specificity
- FFR between 0.75 and 0.80 may indicate ischemia
- FFR > 0.80 is highly likely to be non‑ischemic
* AUC Guidelines reflect the FAME cutoff of 0.80
FFR-Guided Procedures Improved Outcomes
Over Angio-Guided Procedures1
† Relative risk reduction
- The FFR group performed significantly better in MACE-free survival 30 – 360 days
- The FFR group was statistically significant in Death/MI and MACE but improved in all metrics vs. the angio-guided group
FAME II Demonstrated that PCI was
Superior to Medical Therapy with FFR > 0.81
Death, MI, and Revascularization
- FAME II randomized patients with FFR < 0.8 to PCI + MT† or MT compared to patients with FFR > 0.8 who received MT
- 83% Relative risk reduction in urgent revascularization in FFR PCI + MT group
FFR-guided procedures improve outcomes and reduce costs2
- FFR use demonstrated improved overall health outcomes at one year with less MACE, MI, and death
- Savings of $2,385/patient over one year in patients with multi vessel disease
- FFR reduced costly adverse events
- FFE provides accurate diagnosis to reduce costs
* Hospital savings are based on calculations by Boston Scientific.