FFR

Master the Complex - FFR Master the Complex - FFR

Use FFR to Determine the Culprit Lesion

A strong body of clinical evidence supports FFR usage to identify ischemia producing lesions. Partner with Boston Scientific to access a complete set of PCI Guidance tools that will help you master the complex.

What is FFR?

FFR is...

What is FFR? What is FFR?

...the maximum flow down a vessel in the presence of stenosis compared to maximum flow in the hypothetical absence of the stenosis.

FFR <0.80 is the Cutoff Used in Most Clinical Studies (FAME)*

FFR <0.80 is the Cutoff Used in Most Clinical Studies (FAME)* FFR <0.80 is the Cutoff Used in Most Clinical Studies (FAME)*

  • FFR < 0.75 was validated against the 3 gold standard tests to correlate with ischemia with 100% specificity
  • FFR between 0.75 and 0.80 may indicate ischemia
  • FFR > 0.80 is highly likely to be non‑ischemic

* AUC Guidelines reflect the FAME cutoff of 0.80

Clinical Information

FAME I
FFR-Guided Procedures Improved Outcomes
Over Angio-Guided Procedures1

1-year Outcomes

FAME I - 1-Year Outcomes FAME I - 1-Year Outcomes

† Relative risk reduction

  • The FFR group performed significantly better in MACE-free survival 30 – 360 days
  • The FFR group was statistically significant in Death/MI and MACE but improved in all metrics vs. the angio-guided group

FAME II
FAME II Demonstrated that PCI was
Superior to Medical Therapy with FFR > 0.81

Death, MI, and Revascularization

FAME II - Death, MI, and Revascularization FAME II - Death, MI, and Revascularization

  • FAME II randomized patients with FFR < 0.8 to PCI + MT or MT compared to patients with FFR > 0.8 who received MT
  • 83% Relative risk reduction in urgent revascularization in FFR PCI + MT group

Economic Value

FFR Quality Outcomes FFR Quality Outcomes

Quality Outcomes

FFR Financial Health FFR Financial Health

Financial Health

FFR-guided procedures improve outcomes and reduce costs2

  • FFR use demonstrated improved overall health outcomes at one year with less MACE, MI, and death
  • Savings of $2,385/patient over one year in patients with multi vessel disease
  • FFR reduced costly adverse events
  • FFE provides accurate diagnosis to reduce costs

FFR one year cost per patient / annualized savings for hospital FFR one year cost per patient / annualized savings for hospital

FFR use improved health outcomes FFR use improved health outcomes

* Hospital savings are based on calculations by Boston Scientific.

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