SYNERGY Stent offers peace of mind knowing the polymer is fully absorbed between three and four months.2
Long-term data shows promising results with ZERO ARC definite/probable stent thrombosis and exceptionally low target lesion revascularization out to four years.
Four-Year Results: 0% ARC Definite/Probable ST and 1.1% TLR at Four Years1
One NQWMI in the SYNERGY group was periprocedural. The remaining 2 NQWMI in the SYNERGY arm were considered unrelated to the study device: one at day 347 due to anemia and a major GI bleed, and one at day 364 subsequent to respiratory failure in a patient with severe COPD – enzymes were checked indicating that a NQWMI had occurred. The one death was of an unknown cause at day 472 and adjudicated as a Cardiac Death. Safety Population. (PROMUS Element N = 98; SYNERGY N = 92) All p-values are >0.05.
EVOLVE II Diabetes Substudy
12-Month Clinical Results
EVOLVE II DM Clinical Trial. Presented by Stephan Windecker, MD at PCR 2015
^Cutlip et al, Circulation. 2007; 115(17):2344;
* Spontaneous MI was defined as the rise and/or fall of cardiac biomarkers with ≥1 value >99th percentile of the upper reference limit (URL) with ≥1 of the following: symptoms of ischemia, ECG changes, and or evidence of loss of myocardium. Peri-PCI MI was defined by any of the following: i) CK-MB >3X URL within 48 hours, ii) new pathological Q waves, iii) autopsy evidence. All ST were definite.