Significantly Lower PVL than
Evolut™ R / CoreValve™

The LOTUS Valve Platform is designed to minimize Paravalvular Leak (PVL) with a proprietary Adaptive Seal™.

In the REPRISE III High Calcium Cohort, the LOTUS Valve platform had significantly lower PVL than Evolut R / CoreValve in patients with high calcium burden. This data is consistent with the superior PVL performance of LOTUS in the broader REPRISE III Trial.

PVL Rates Across Studies is consistently low PVL Rates Across Studies is consistently low

Presented by R. Makkar, MD at PCR LV 2017 

PVL Rates Across Studies

Consistently low rates of PVL

PVL Rates Across Studies is consistently low PVL Rates Across Studies is consistently low

1 Presented by D. Blackman, MD at PCR 2017 
2 Presented by D. Walters, MD at ACC 2017
3 Presented by I. Meredith, MD at PCR LV 2016 
4 Presented by N. Van Mieghem, MD at PCR 2017 
5 Presented by T. Feldman, MD at PCR 2017