Video showing how the Eluvia Drug-Eluting Vascular Stent was designed for better patient outcomes

Through its polymer-based drug delivery, Eluvia transfers the majority of the drug to the tissue and minimizes downstream particulates.

Jay Kokate, R&D Director, Explains How It Works

Restenosis in the SFA

Due to the biological environment and significant mechanical forces in the SFA, the timing of restenosis is longer than in other anatomies. As a result, engineers for the Eluvia Drug-Eluting Stent needed to identify the right formulation of paclitaxel and polymer to tune an elution curve that would help ensure the drug is available when restenosis is most likely to occur.

 

Chart showing the clinical history of restenosis in the SFA

Clinical History of Restenosis1

Sustained Drug Release Beyond 12 Months

The Eluvia Drug-Eluting Stent is the only therapy for the SFA designed to match the release of paclitaxel to the restenotic process for better healing and patency.

Eluvia sustains drug concentrations in the lesion to match the restenotic process in the SFA
  1. Iida, O. et al. Catheterization and Cardiovascular Interventions. 2011; 78:611–617.
  2. Based on preclinical pharmacokinetic analysis for Zilver PTX. Dake MD, et al. J Vasc Interv Radiol. 2011;22(5):603-610.
  3. Based on preclinical pharmacokinetic analysis for three Drug-Coated Balloons (IN.PACT Pacific, Lutonix, Ranger). Gongora CA, et al. JACC Cardiovasc Interv. 2015 Jul;8(8):1115-1123. doi: 10.1016/j.jcin.2015.03.020.
  4. Based on preclinical pharmacokinetic analysis for Eluvia. Data on file at Boston Scientific.
Dr. Juan Granada discusses how sustained drug release sets the Eluvia Stent System apart from other vascular stents

“The Eluvia stent is unique in the way in which the polymer is essentially designed and fine-tuned to produce a sustainable release of paclitaxel over time.”

Juan Granada, MD
President and CEO, Cardiovascular Research Foundation
New York, NY

Video showing how the Eluvia Drug-Eluting Vascular Stent was designed for better patient outcomes

Designed for Better Patient Outcomes

See how the Eluvia Drug-Eluting Stent leverages proven Boston Scientific technologies to lead the way in the emerging world of drug-eluting therapies for the SFA and help improve patients’ lives.

Stent Design & Delivery

Built on the foundation of the next-generation Innova™ Stent platform, the Eluvia Drug-Eluting Stent is designed to provide uniform scaffolding for drug delivery while optimizing flexibility, radial strength and fracture resistance.

Close-up of the Eluvia Drug-Eluting Stent
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