Bronchial Thermoplasty

Bronchial Thermoplasty

Bronchial Thermoplasty (BT) is a safe procedure clinically proven to provide a long-lasting reduction in asthma attacks for patients with severe asthma 4,5. This brochure explains how the BT procedure works to reduce asthma attacks, and what you should expect if you and your doctor decide that BT is right for you.

BT, delivered by the Alair™ System, works by safely applying mild heat inside the airways to reduce excessive smooth muscle. - With Asthma -

Airway smooth-muscle tissue surrounds the walls of the airways. People with severe asthma have more airway smooth muscle than people who don’t have asthma.1-3

Increased airway smooth muscle

Fewer asthma attacks means less need for the associated oral steroid treatment and its side effects - BT-treated airway.

BT reduces the amount of excess smooth-muscle tissue in the airways. With less of this tissue, the airways constrict less, breathing is easier, and there is less likelihood of an asthma attack.4

Reduced airway smooth muscle limits airway constriction and asthma symptoms

Your doctor will refer you to a BT Clinic for consultation with a BT-treating physician. BT is indicated for patients who:
• Are 18 years or older
• Are able to safely undergo a bronchoscopy procedure
• Have severe persistent asthma that is not well controlled with standard medications alone. This can include:

— Patients who have been chronically using oral corticosteroids
— Candidates for Anti-lgE

Patients whose asthma is not well controlled may:

  • Experience two or more asthma attacks per year
  • Have impaired quality of life due to asthma (assessed by metrics like AIS-6, ACT, AQLQ*)

Your doctor will notify you if you are a candidate for BT, and if applicable, when BT treatment will begin. As with any procedure, there are risks, and individual results may vary. The most common adverse event of BT is a temporary worsening of respiratory-related symptoms. These events typically occur within one day of the BT procedure and usually resolve within a week with proper care. There is a small risk (3.4% per procedure) that symptoms may require hospitalization.6

* Some useful tools are the clinically validated Asthma Impact Survey™ (AIS-6), Asthma Control Test (ACT), and Asthma Quality of Life Questionnaire (AQLQ) that can be administered to patients to help assess whether asthma is limiting daily activities and impacting quality of life.

• BT is performed by a specially trained pulmonologist, using a device called the Alair System
• No incision is needed because the procedure is performed with a bronchoscope inserted through the mouth or nose

Delivering mild heat to airways

• You will be monitored after each procedure and discharged on the same day if your vital signs and lung function are near normal levels
• Plan a follow-up office visit 2 to 3 weeks after the BT procedure to determine if you are ready for your next procedure
• After all 3 procedures are performed, the BT treatment is complete. You do not have to be retreated with BT
• You will return to your regular doctor to continue managing your asthma

Ask your doctor or BT-treating physician for more details on what to expect during and after the BT procedure.

NOTE: BT is meant to work with your current asthma reliever and controller medications. It is not a replacement for your current medications.

  • BT is a procedure performed in 3 sessions, scheduled 3 weeks
  •  apart, to ensure safety and optimal results every step of the way.
    Each session treats airways in a different part of the lung:

1. Right lower lobe / 2. Left lower lobe / 3. Upper lobes

• Procedures are routinely performed under moderate sedation and typically completed in less than an hour.

The safety and effectiveness of BT has been proven out to 5 years. In a clinical trial, there was no significant long-term adverse effect to the airways and no clinically significant deterioration in lung function.4,5

“Intended purpose approved under Medical Device Directive 93/42/EEC: The Alair Bronchial Thermoplasty System is indicated for the treatment of asthma in patients 18 years and older.” Information not intended for distribution in France