Product Information
A Proven Stent
The Express² Stent platform offers excellent deliverability and conformability.
- Excellent deliverability allows for treatment of a variety of patient and lesion types.1
- Excellent conformability allows the stent to mold to the natural contours of the vessel wall.1
- Broad working range facilitates precise deployment and sizing flexibility, making it easy to achieve full stent apposition.1
A Reliable Polymer
The TAXUS stent uses Translute™ Polymer, a proprietary polymer carrier technology, to control drug release.
- The durable Translute Polymer protects the drug and maintains coating integrity during preparation, delivery, and stent expansion.
- The polymer controls the release of paclitaxel, which may allow for consistent drug release and more uniform drug distribution.2
An Effective Drug
The unique properties of paclitaxel may contribute to the efficacy of the TAXUS Stent.
- Paclitaxel's multi-functional effects, stabilize microtubules and inhibit activities that contribute to restenosis.3
- Paclitaxel is highly lipophilic, which may contribute to more uniform drug distribution.4
- At the dose used in the TAXUS Stent, paclitaxel does not impede the natural healing process.5
Device Illustration
Additional Information
Sources:
1Boston Scientific Bench Tests (data on file).
2"Paclitaxel release from inert polymer material-coated stents curtails coronary in-stent restenosis in pigs" - Rogers et al. - Circulation. 2000; 102 (18 Supplement):II566-II567.
3"The Multifunctional Effects of Paclitaxel on the Neointimal Cascade: A Close Look at the Role of Microtubules" - Boston Scientific (2002).
4"Arterial Paclitaxel Distribution and Deposition" - Circulation Research. 2000; 86:879-884.
5"Paclitaxel Inhibits Arterial Smooth Muscle Proliferation and Migration In Vitro and In Vivo Using Local Drug Delivery" - Axel et al. - Circulation. 1997; 96:636-645.
