INSIGNIA® Pacing Systems

Product Information

Insignia Ultra

• Minute Ventilation (MV) provides a physiologic response to increased levels of work
• Accelerometers respond only to the frequency and intensity of motion; cannot respond to increases in workload
• MV Blended Sensor combines the strengths of both sensors

Accelerometer-indicated rate

vs. chronotropically competent trend plot

Minute Ventilation blended sensor vs. chronotropically competent trend plot

Automatic Capture – Beat to Beat Operation…Any lead, Any polarity

• Increased longevity - Automatically adjusts the pacing amplitude according to patient's changing ventricular pacing thresholds
• Patient Safety - Confirms ventricular capture on a beat-to-beat basis and provides a back-up safety pulse if necessary
• Ease of Use – One button activation

Ventricular Rate Regulation (VRR) – Designed to manage irregular ventricular intervals during atrial tachyarrhythmias

• Goal is to reduce V-V cycle length variability during conducted atrial arrhythmias by moderating the ventricular pacing rate

• In DDD(R) modes only during an ATR mode switch episode, but is always available in VVI(R) modes

Sudden Brady Response (SBR) – Designed to respond to a sudden drop in heart rate that can occur with neurocardiogenic syncope

• Responds to a patient's sudden drop in intrinsic (atrial) rates by applying dual-chamber pacing at an elevated rate

Arrhythmia Logbook – Allows clinicians to choose which events will trigger stored electrograms (EGMs)

• Logs a detailed record of up to 40 patient arrhythmias
• Information includes: Date, Start time, Onset rate, Maximum rate, and Trigger

Stored Intercardiac Electrograms (EGMs) – Clear and precise EGMs

•  Separate atrial and ventricular channels with 110 seconds of storage

• Onset and event markers to simplify interpretation
• Less than 0.5% impact on device longevity
• Programmable feature allows patients to trigger their own EGMs for event recording

Insignia Plus

Features:

•  MV Blended Sensor

•  AV Search Hysteresis

•  VRR

•  SBR

•  Arrhythmia Logbook

•  EGMs

Insignia Entra

Features:

• Accelerometer Sensor
• Dynamic AV Delay
• Arrhythmia Logbook
• EGMs

^{(1) Chronotropic competence is defined by: Wilkoff BL, Corey J, Blackburn G. A mathematical model of cardiac chronotropic response to exercise. J. Electrophysio . 1989;3(3): 176-180. Refer to Physician's System Guide for more information on adaptive-rate therapy. Additional clinical performance was assessed using INSIGNIA Ultra clinical data with the AutoLifestyle feature programmed On. Data on file.}

Device Illustration